CAS: 32383-76-9; (6Ar,11Ar)-9-Methoxy-6A,11A-Dihydro-6H-Benzofuro[3,2-C]Chromen-3-Ol

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CAS号131887-80-4 (2R,3S)-2,7,4'-... | CAS号1890-99-9 2'-Hydroxyformo... | CAS号108-46-3 间苯二酚 | CAS号32383-76-9 美迪紫檀素 | CAS号6496-89-5 2,4-二甲氧基苯乙酸 | CAS号770722-02-6 2,7-dihydroxy-4... | CAS号485-72-3 芒柄花黄素 | CAS号32383-76-9 美迪紫檀素 | CAS号33983-39-0 (6aS,11aS)-9-me... | CAS号1690-62-6 4'-O-甲基香豆雌酚

📜刺芒柄花素 反应生成 美迪紫檀素
参考文献:Catalytic Specificity Of Pea O-Methyltransferases Suggests Gene Duplication For (+)-Pisatin Biosynthesis
标题:Catalytic Specificity Of Pea O-Methyltransferases Suggests Gene Duplication For (+)-Pisatin Biosynthesis
摘要:S-Adenosyl-L-Methionine: 2-Hydroxyisoflavanone 4'-O-Methyltransferase (Hi4'Omt) Methylates 2,7,4'-Trihydroxyisoflavanone To Produce Formononetin,An Essential Intermediate In The Synthesis Of Isoflavonoids With Methoxy Or Methylenedioxy Groups At Carbon 4' (Isoflavone Numbering). Hi4'Omt Is Highly Similar (83% Amino Acid Identity) To (+)-6A-Hydroxymaackiain 3-O-Methyltransferase (Hmm),Which Catalyzes The Last Step Of (+)-Pisatin Biosynthesis In Pea. Pea Contains Two Linked Copies Of Hmm With 96% Amino Acid Identity. In This Report,The Catalytic Activities Of The Licorice Hi4'Omt Protein And Of Extracts Of Escherichia Coli Containing The Pea Hmm1 Or Hmm2 Protein Are Compared On 2,7,4'-Trihydroxyisoflavanone And Enantiomers Of 6A-Hydroxymaackiain. All These Enzymes Produced Radiolabelled 2,7-Dihydroxy-4'-Methoxyisoflavanone Or (+)-Pisatin From 2,7,4'-Trihydroxyisoflavanone Or (+)-6A-Hydroxymaakiain When Incubated With [methyl-C-14]-S-Adenosyl-L-Methionine. No Product Was Detected When (-)-6A-Hydroxymaackiain Was Used As The Substrate. Hiwomt And Hmmi Showed Efficiencies (Relative V-Max/k-M) For The Methylation Of 2,7,4'-Trihydroxyisoflavanone 20 And 4 Times Higher Than For The Methylation Of (+)-6A-Hydroxymaackiain,Respectively. In Contrast,Hmm2 Had A Higher V-Max And Lower K-M On (+)-6A-Hydroxymaackiain,And Had A 67-Fold Higher Efficiency For The Methylation Of (+)-6A-Hydroxymaackiain Than That For 2,7,4'-Trihydroxyisoflavanone. Among The 15 Sites At Which Hmmi And Hmm2 Have Different Amino Acid Residues,11 Of The Residues In Hmm1 Are The Same As Found In Hi4'Omts From Three Plant Species. Modeling Of The Hmm Proteins Identified Three Or Four Putative Active Site Residues Responsible For Their Different Substrate Preferences. It Is Proposed That Hmm I Is The Pea Hiwomt And That Hmm2 Evolved By The Duplication Of A Gene Encoding A General Biosynthetic Enzyme (Hiwomt). (C) 2006 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Phytochem.2006.09.010

专利信息

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人：NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

专利号:US-9238821-B2
优先权日:2009-04-14
标题 :Metabolic engineering for plant disease resistance
发明人：LI WENSHENG; UPPALAPATI SRINIVASA RAO; MYSORE KIRANKUMAR S; DIXON RICHARD A; SUMNER LLOYD W
权利人:LI WENSHENG; UPPALAPATI SRINIVASA RAO; MYSORE KIRANKUMAR S; DIXON RICHARD A; SUMNER LLOYD W; SAMUEL ROBERTS NOBLE FOUND INC
摘要:The invention provides methods and compositions for making a dicotyledonous plant that is susceptible to Phymatotrichopsis Root Rot (PRR) more resistant to PRR, by metabolic engineering of the plant's flavonoid and isoflavonoid biosynthetic pathways. Thus, methods for increasing the synthesis and accumulation of medicarpin and/or 7,4′-dihydroxyflavone in plants such as alfalfa are provided.