CAS: 2260-50-6; 2-Acetoxy-N,N,N-Trimethylethan-1-Aminium Iodide

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CAS号627-10-1 2-碘-1-乙醇乙酸酯 | CAS号75-50-3 三甲胺 | CAS号71-50-1 acetate

合成工艺路线路线简述

    📜2-碘-1-乙醇乙酸酯,三甲胺置于乙醚体系中,化学反应生成碘化乙酰胆碱
    参考文献:Iwin,Zhurnal Obshchei Khimii,1958,Vol. 28,P. 1332; Engl. Ausg. S. 1390
    标题:Iwin,Zhurnal Obshchei Khimii,1958,Vol. 28,P. 1332; Engl. Ausg. S. 1390

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    专利信息


    专利号:US-6160128-A
    优先权日:1997-12-22
    标题:Tritioacetylating reagents and processes for preparation thereof
    发明人:SALJOUGHIAN MANOUCHEHR; MORIMOTO HIROMI; WILLIAMS PHILIP G; THAN CHIT
    权利人:UNIV CALIFORNIA
    摘要:Novel acetylating and tritioacetylating reagents suitable for preparation of nonlabelled and radiolabelled organic compounds. N-acetoxynaphthalimide, N-tritioacetoxyphthalimide, N-tritioacetoxysuccinimide, N-tritioacetoxynaphthalimide and processes of their preparation. The invention also concerns synthesis of nonlabelled acetylated and tritioacetylated organic compounds from precursors containing a free --NH 2 , --SH or --OH group.

    专利号:RU-1767843-C
    优先权日:1990-06-15
    标题 :Method of synthesis of biologically active substance on the basis of n,n-dimethyl- (2-n',n'- dimethylaminomethylpyridyl-3)-carbamate salt and styrenevinylbenzene sulfocationite showing inhibition effect on choline esterases

    专利号:US-8993696-B2
    优先权日:2011-04-27
    标题 :Method for producing polymer particles
    发明人:HIRATANI TAKAYUKI; KOJI SHINNOSUKE; NAKAHAMA KAZUMICHI
    权利人:HIRATANI TAKAYUKI; KOJI SHINNOSUKE; NAKAHAMA KAZUMICHI; CANON KK
    摘要:A method for producing polymer particles includes a suspension step of suspending a first liquid mixture containing an oily olefin monomer, a radical polymerization initiator, and an iodine molecule in a second liquid mixture containing water and an iodide ion to prepare a suspension containing an oil droplet having the first liquid mixture; a synthesis step of synthesizing an iodine compound by allowing a radical generated by cleavage of the radical polymerization initiator to react with the iodine molecule in the oil droplet; and a polymerization step of polymerizing the oily olefin monomer in the oil droplet.

    专利号:US-9115221-B2
    优先权日:2012-10-24
    标题 :Method for producing polymer particles
    发明人:HIRATANI TAKAYUKI; KOJI SHINNOSUKE; NAKAHAMA KAZUMICHI
    权利人:CANON KK
    摘要:A method for producing polymer particles includes a suspension step of suspending a first liquid mixture containing an oily olefin monomer and a radical polymerization initiator in a second liquid mixture containing water, an iodide ion, and an iodine molecule, to prepare a suspension in which an oil droplet containing the oily olefin monomer and the radical polymerization initiator is dispersed in the water containing the iodide ion and the iodine molecule, a synthesis step of synthesizing an iodine compound by allowing a radical generated by cleavage of the radical polymerization initiator to react with the iodine molecule in the oil droplet, and a polymerization step of polymerizing the oily olefin monomer in the oil droplet.

    专利号:CN-104292280-A
    优先权日:2014-10-09
    标题:A kind of aminoglucothiazole derivative and its synthesis method and application

    专利号:CN-115636830-B
    优先权日:2022-10-27
    标 题 :A kind of matrine derivative and its synthesis method and use

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    主要参考文献


    1: Yoder RM, Chan JHM, Taube JS. Acetylcholine contributes to the integration of self-movement cues in head direction cells. Behav Neurosci. 2017 Aug;131(4):312-24. doi: 10.1037/bne0000205.
    2: Williamson PT, Verhoeven A, Miller KW, Meier BH, Watts A. The conformation of acetylcholine at its target site in the membrane-embedded nicotinic acetylcholine receptor. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18031-6. Epub 2007 Nov 7.
    3: Spence VA, Khan F, Kennedy G, Abbot NC, Belch JJ. Acetylcholine mediated vasodilatation in the microcirculation of patients with chronic fatigue syndrome. Prostaglandins Leukot Essent Fatty Acids. 2004 Apr;70(4):403-7. Review.

    合成参考文献


    摘要:International Journal of Neuropharmacology., 8(131), 1969 []
    参考文献:10.1134/s1607672906020098
    摘要:Rozengart EV, Basova NE. Effect of aliphatic alcohols and pH on different types of serum cholinesterase reactivity. Doklady Biochemistry and Biophysics. 2006 Apr;407(1):77–82. doi: 10.1134/s1607672906020098.
    参考文献:10.1186/s12906-020-03047-7
    摘要:Olasehinde TA, Olaniran AO, Okoh AI. Sulfated polysaccharides of some seaweeds exhibit neuroprotection via mitigation of oxidative stress, cholinergic dysfunction and inhibition of Zn – induced neuronal damage in HT-22 cells. BMC Complementary Medicine and Therapies. 2020 Aug 14;20(1):251. doi: 10.1186/s12906-020-03047-7.
    参考文献:10.1007/bf00318751
    摘要:Spit BJ, Bretschneider F, Hendriksen EGJ, Frieke Kuper C. Ultrastructure of free nerve endings in respiratory and squamous epithelium on the rat nasal septum. Cell and Tissue Research. 1993 Nov;274(2):329–35. doi: 10.1007/bf00318751.
    参考文献:10.1007/s00204-006-0144-7
    摘要:Baireddy P, Mirajkar N, Nallapaneni A, Singleton N, Pope CN. Effects of combined, multiple stressors on pyridostigmine-induced acute toxicity in rats. Arch Toxicol. 2007 Apr;81(4):283–9. doi: 10.1007/s00204-006-0144-7.
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