CAS: 140-55-6; (3S,6S)-6-Propylpiperidin-3-Ol
- 英文名称(3S,6S)-6-Propylpiperidin-3-Ol
- 中文名称(3S,6S)-6-丙基哌啶-3-醇
- 其它别名3-Piperidinol,6-propyl-, (3S-trans)-; Pseud°Conhydrine (6CI,7CI,8CI); (+)-Pseud°Conhydrine; y-Conhydrine
- CAS编号140-55-6
- FDA UNII编号:90282P2S37
- 分子式:C8H17NO分子量:143.229
- 产品CID: 2623462
- 产品分类有机原料 → 生物碱及其衍生物
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: BQSAUYXITCMAKS-YUMQZZPRSA-N
- 1S/C8H17NO/c1-2-3-7-4-5-8(10)6-9-7/h7-10H,2-6H2,1H3/t7-,8-/m0/s1
- 计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数2.0
MSDS等安全信息
合成工艺路线路线简述
📜3-羟基吡啶置于palladium Dihydroxide 盐酸,甲醇,4-二甲氨基吡啶,Sodium Tetrahydroborate,氢气,碳酸氢钠,Potassium Carbonate,三乙胺,Zinc(II) Chloride体系中,用 甲醇,二氯甲烷 用作溶剂,-80.0~25.0 °C,101.33 Kpa 条件下,反应 73.5H,反应生成(3S,6S)-6-丙基哌啶-3-醇
参考文献:Novel Reduction Of 3-Hydroxypyridine And Its Use In The Enantioselective Synthesis Of (+)-Pseudoconhydrine And (+)-N-Methylpseudoconhydrine
标题:Novel Reduction Of 3-Hydroxypyridine And Its Use In The Enantioselective Synthesis Of (+)-Pseudoconhydrine And (+)-N-Methylpseudoconhydrine
摘要:在氯甲酸苄酯存在下,用硼氢化钠还原 3-羟基吡啶,得到 1-苄氧羰基-5-羟基-2-哌啶,然后通过脂肪酶介导的动力学分解,分五个步骤转化为(+)-假酸酐和(+)-N-甲基假酸酐.
Doi:10.1039/cc9960001433
海关参考信息
- 2905122000-异丙醇
2922110001-单乙醇胺
2905142000-仲丁醇
2901100000-饱和无环烃 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Stereoselective Route Towards 2,5-Disubstituted Piperidine Alkaloids. Synthesis Of (+)-Pseudoconhydrine And (+/-)-Epi-Pseudoconhydrine作者:Joakim Löfstedt,Helena Pettersson-Fasth,Jan-E Bäckvall |发布日期:2000.4
摘要:This Paper Describes A New General Approach Towards Functionalized Piperidine Alkaloids, Based On The Stereo- And Regioselective Palladium(0)-Catalyzed Nucleophilic Ring-Opening Of Vinyl Epoxides By Nitrogen Nucleophiles. The Latter Reaction Provides Access To Stereodefined Anti And Syn Aminoalcohol Derivatives, 1-Benzyloxy-5-(P-Toluenesulfonamido)-3-Alken-2-Ols (5), Which Were Transformed To (+)-Pseudoconhydrine
合成参考文献
摘要:Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif, Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948, -(593), 1948
📝 需求与反馈
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