CAS: 6436-90-4; Ethyl 2-(Benzylamino)Acetate

相似化合物

6344-42-9 77385-90-1 62004-76-6

上下游产品

CAS号105-36-2 溴乙酸乙酯 | CAS号100-46-9 苄胺 | CAS号623-73-4 重氮乙酸乙酯 | CAS号105-39-5 氯乙酸乙酯 | CAS号459-73-4 2-胺基乙酸乙酯 | CAS号623-33-6 甘氨酸乙酯盐酸盐 | CAS号100-39-0 溴化苄 | CAS号100-52-7 苯甲醛 | CAS号3287-99-8 苄胺盐酸盐 | CAS号100-44-7 氯化苄 | CAS号50866-56-3 1-苄基-3,5-哌啶二酮 | CAS号39514-19-7 1-苄基-3-氧杂-4-哌啶甲酸乙酯 | CAS号477220-33-0 (S)-4-苯甲基-2-哌嗪乙醇 | CAS号324750-04-1 (S)-1-苄基-3-乙基哌嗪 | CAS号52763-21-0 N-苄基-3-氧代哌啶-4-羧... | CAS号15057-43-9 1-苄基-5-羟基-1,6-二... | CAS号17136-36-6 N-苄基甘氨酸 | CAS号17136-35-5 2-(苄基氨基)乙酸甲酯 | CAS号459-73-4 2-胺基乙酸乙酯 | CAS号220663-44-5 1-BENZYL-2(S)-I...

马尿酸乙酯置于acethylacetonato(1,5-Cyclooctadiene)Rhodium(I),苯硅烷体系中,用 四氢呋喃 作为反应溶剂,化学反应 24.0H,以75%的收率获得产物n-苄基甘氨酸乙酯
参考文献:普通和选择性铑催化的苯基硅烷还原酰胺,N-酰基氨基酯和二肽
标题:普通和选择性铑催化的苯基硅烷还原酰胺,N-酰基氨基酯和二肽
摘要:本文介绍了使用简单的[rh(acac)(cod)]将功能化的酰胺(包括n-酰基氨基酯和二肽)选择性还原为相应的胺.在不同的敏感功能部分的存在下,该催化剂表现出优异的化学选择性.
DOI:10.1002/chem.201600535

专利信息

专利号:WO-2023118363-A1
优先权日:2021-12-22
标题:Method for the synthesis of a carbonyl-functionalised adduct
发明人：GODEHARD SIMON P; PELZER ALEXANDER
权利人:BRAIN Biotech AG
摘要:The invention relates to a method for the synthesis of a carbonyl-functionalised adduct.

专利号:EP-0535155-B1
优先权日:1990-06-14
标 题:Libraries of modified peptides with protease resistance
发明人：BARTLETT PAUL A; SANTI DANIEL; SIMON REYNA
权利人:CHIRON CORP; UNIV CALIFORNIA
摘要:Peptoids are provided which are polymers comprised of monomer units wherein the monomer units include at least some substitute amino acids and may include conventional amino acids. The peptoids can be synthesized in large numbers so as to provide libraries of peptoids which can be screened in order to isolate peptoids of desired biological activity. Certain peptoids are designed to mimic as closely as possible the activity of known proteins. Other peptoids are designed so as to have greater or lesser activity than known proteins and may be designed so as to block known receptor sites and/or elicit a desired immunogenic response and thereby act as vaccines. A range of different amino acid substitutes are disclosed, as are their methods of synthesis and methods of using such amino acid substitutes in the synthesis of peptoids and peptoid libraries. Methods of screening the libraries in order to obtain desired peptoids of a particular biological activity are also disclosed. The peptoids are preferably linked to a pharmaceutically active drug forming a conjugate with increased binding affinity to a particular biological receptor site.

专利号:US-6075121-A
优先权日:1990-05-15
标 题 :Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such
发明人：SIMON REYNA J; BARTLETT PAUL A; SANTI DANIEL V
权利人:CHIRON CORP
摘要:Peptoids are provided which are polymers comprised of monomer units wherein the monomer units include at least some substitute amino acids and may include conventional amino acids. The peptoids can be synthesized in large numbers so as to provide libraries of peptoids which can be screened in order to isolate peptoids of desired biological activity. Although the peptoids may include amino acids, they preferably include only substituted amino acids and are designed in a manner so as to have a particular biological activity. Certain peptoids are designed to mimic as closely as possible the activity of known proteins. Other peptoids are designed so as to have greater or lesser activity than known proteins and may be designed so as to block known receptor sites and/or elicit a desired immunogenic response and thereby act as vaccines. In that the peptoids are comprised of substitute amino acids they can be designed to have structures which natural proteins cannot conform to. A range of different amino acid substitutes are disclosed, as are their methods of synthesis and methods of using such amino acid substitutes in the synthesis of peptoids and peptoid libraries. Methods of screening the libraries in order to obtain desired peptoids of a particular biological activity are also disclosed. The peptoids are preferably linked to a pharmaceutically active drug forming a conjugate with increased binding affinity to a particular biological receptor site.

专利号:US-2010036120-A1
优先权日:2006-01-25
标题 :Novel method for synthesis of 1,4-morpholine-2,5-diones

专利号:US-8338565-B2
优先权日:2008-08-20
标 题 :Macrocyclic compounds for inhibition of tumor necrosis factor alpha
发明人：LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P
权利人:LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P; ENSEMBLE THERAPEUTICS CORP
摘要:Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.

专利号:IT-PD20110153-A1
优先权日:2011-05-13
标 题 :METHOD OF SYNTHESIS OF CARBON NANOTUBES FUNCTIONALIZED BY CYCLE ADDS IN CONTINUOUS FLOW AND APPARATUS FOR THE SAME