欧盟法规
ECHA物质C&L通报上下游产品
1-bromo dodecane 1-thi°Cyanatodecane didecyl disulfide perfluorodecane sulfonylfluoride decane-1-sulfonanilide Aethyl-4-decansulfonamidobenzoat N'-(decylsulfonyloxy)-4-nitrobenzimidamide 合成工艺路线路线简述
- 合成目标产物 1-Decanesulfonyl Chloride 主要起始原料 Didecyl Disulfide
- (文献来源)合成步骤主要原料 Didecyl Disulfide
📜癸基溴置于水,Sodium Sulfite体系中,化学反应生成 1-癸烷磺酰氯
参考文献:Burdon Et Al.,Journal Of The Chemical Society,1957,P. 2574,2576
标题:Burdon Et Al.,Journal Of The Chemical Society,1957,P. 2574,2576
专利信息
专利号:US-2003153783-A1
优先权日:1999-06-30
标题:Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid
发明人:GIANNESSI FABIO; DELL UOMO NATALINA; TINTI MARIA ORNELLA; DE ANGELIS FRANCESCO
权利人:SIGMA TAU IND FARMACEUTI
摘要:A process is described for the preparation of R or S aminocarnitine, R or S phosphonium aminocarnitine and R and S 3,4 diaminobutanoic acid, and their derivatives with the following formula: n n n where Y is as described in the attached description, starting from aspartic acid with the same configuration as the desired compounds. This process is advantageous from the industrial point of view in terms of the type of reactants used, the reduced volumes of solvents and the possibility of avoiding purification of the intermediate products.
专利号:US-6228988-B1
优先权日:1995-02-24
标题:Synthesis of hydroxamic acid derivatives
发明人:FLOYD CHRISTOPHER DAVID; LEWIS CHRISTOPHER NORMAN
权利人:BRITISH BIOTECH PHARM
摘要:The present invention describes processes for preparing desired synthetic products that comprise a covalently bonded hydroxamic acid group -CONHOH by forming a mixture of a liquid reaction medium and a solid phase reaction product that carries a plurality of moieties of formula (A1) or (B1):where X is a residual, non-hydroxamate partial structure of the desired synthetic product, P1 is hydrogen or an amino-protecting group, P2 is hydrogen or a hydroxyl protecting group, and the bond designated (a) covalently links the moieties (A1) or (B1) to the residue of a solid substrate; by cleaving the bond designated (a) in the resultant mixture; and by separating the resultant liquid reaction phase from the resultant reaction solids to recover the desired synthetic product.
专利号:US-6822115-B2
优先权日:1999-06-30
标 题:Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid
发明人:GIANNESSI FABIO; DELL UOMO NATALINA; TINTI MARIA ORNELLA; DE ANGELIS FRANCESCO
权利人:SIGMA TAU IND FARMACEUTI
摘要:R or S aminocarnitine, R or S phosphonium aminocarnitine and R and S 3,4 diaminobutanoic acid, and their derivatives are prepared using n starting from aspartic acid with the same configuration as the desired compounds. This process is advantageous from the industrial point of view in terms of the type of reactants used, the reduced volumes of solvents and the possibility of avoiding purification of the intermediate products.
专利号:US-6528684-B1
优先权日:1999-06-30
标题 :Synthesis of (R) and (S) -aminocarnitine and their derivatives starting from D- and L-aspartic acid
发明人:GIANNESSI FABIO; DELL UOMO NATALINA; TINTI MARIA ORNELLA; DE ANGELIS FRANCESCO
权利人:SIGMA TAU IND FARMACEUTI
摘要:R or S aminocarnitine and their derivatives with formula (I)where Y is as described in the description, starting with aspartic acid with the same configuration as the aminocarnitine desired. This process has advantage in the type of reactants used, reduced volumes of solvents and the possibility of avoiding purification of intermediate products.
专利号:US-2003153784-A1
优先权日:1999-06-30
标题 :Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid
专利号:US-6093798-A
优先权日:1995-02-24
标题 :Synthesis of hydroxamic acid derivatives