CAS: 6027-89-0; (2S,3S,4R,5S)-2,3,4,5,6-Pentahydroxyhexanal

上下游产品

CAS号87-79-6 L-山梨糖 | CAS号17598-82-2 L-塔格糖 | CAS号5934-56-5 (2R,3S,4R,5S)-2... | CAS号35784-84-0 D-glycero-L-glu... | CAS号882983-01-9 (2R,3R,4S,5R,6R... | CAS号689208-16-0 D-glycero-D-gal...

📜Tert-Butyl-((1R,2S,6S,7R,9S)-4,4-Dimethyl-3,5,8,10-Tetraoxa-Tricyclo[5.2.1.02,6]Dec-9-Ylmethoxy)-Dimethyl-Silane置于三氟乙酸体系中,用 四氢呋喃 作为反应溶剂,以72%的收率获得产物古洛糖
参考文献:使用光化学脱羰的碳水化合物合成
标题:使用光化学脱羰的碳水化合物合成
摘要:利用光化学脱羰反应作为关键步骤,使用含有双环[3.2.1]辛烷骨架的手性结构单元,已经开发了一条通往醛糖,核糖和lyxose,醛己糖,Talose和gulose的新途径.
DOI:10.1016/s0040-4039(01)01874-3

专利信息

专利号:US-2024409571-A1
优先权日:2023-06-08
标 题:Chemoenzymatic synthesis of n-acetylated gangliosides and glycosphingosines
发明人：CHEN XI; YU HAI; MISHRA BIJOYANANDA; ZHENG ZIMIN; AGRAHARI ANAND KUMAR; GUCCHAIT ARIN
权利人:UNIV CALIFORNIA
摘要:Described herein are novel stable 9-N-, 8-N-, and 7-N-acetyl analogues of instable 9-O-acetyl, 8-O-acetyl, and 7-O-acetyl b-series gangliosides and glycosphingosines, including GD3, GD2, GD1b, GT1b, GQ1b, and their glycosphingosines. Chemoenzymatic methods for the production of the stable 9-N-, 8-N-, and 7-N-acetyl analogues are also described herein.

专利号:US-2023212216-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins
发明人：MORRIS ALEXANDER REDFERN; SUTOV GRIGORIJ; BRUNE KARL DIETRICH
权利人:GENIE BIOTECH UK LTD
摘要:Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.

专利号:US-2016122450-A1
优先权日:2013-05-08
标题:Synthesis of a substituted furan
发明人：ZHANG YUGEN; TEONG SIEW PING; YI GUANGSHUN
权利人:AGENCY SCIENCE TECH & RES
摘要:The present invention provides a polymer comprising an aliphatic backbone having a plurality of aromatic rings bonded thereon, said plurality of aromatic rings comprising a first aromatic ring type that has an alkyl halide group substitution on the aromatic ring and a second aromatic ring type that has an optionally substituted ammonium halide group substitution on the aromatic ring. The present invention also provides a method for making an optionally substituted furan, the method comprising the step of subjecting a sugar to a dehydration reaction in the presence of a catalyst comprising said polymer.

专利号:WO-03040139-A1
优先权日:2001-11-06
标 题:Diastereoselective process for the preparation of the antiviral agent4-amino-1-(2r-hydroxymethyl-[1,3]oxathiolan-5s-yl)-1h-pyrimidin-2-one
发明人：BOTTA MAURIZIO; CRESCENZI CRISTINA; MANCINETTI DANIELE; POMPEI MARCO; BONIFACIO FAUSTO
权利人:RECORDATI CHEM PHARM; BOTTA MAURIZIO; CRESCENZI CRISTINA; MANCINETTI DANIELE; POMPEI MARCO; BONIFACIO FAUSTO
摘要:Process for the synthesis of 4-amino-1-(2R-hydroxymethyl - [1,3]oxathiolan-5S-yl)-1H-pyrimidin-2-one (LAMIVUDINE) comprising the reduction of 2-(R)-(4'-(R)acetonyl)-5-oxo-1,3-oxathiolan to give 2-(R)-(4'-(R)-acetonyl)-5-hydroxy-1,3-oxathiolan.

专利号:US-2006156431-A1
优先权日:2003-07-18
标题 :L-gulose dependent vitamin C synthesis
发明人：WOLUCKA BEATA
权利人:UNIV GENT
摘要:The present invention relates to L-gulose dependent vitamin C synthesis. More specifically, the present invention relates to a synthesis pathway of vitamin C, comprising the formation of GDP-L-gulose by GDP-mannose 3″,5″-epimerase, and subsequent transformation into L-gulose and L-ascorbic acid.

专利号:US-5278301-A
优先权日:1990-03-23
标 题:Route to glycals in the allal and gulal series
发明人：HALCOMB RANDALL L; DANISHEFSKY SAMUEL J; WITTMAN MARK D
权利人:UNIV YALE
摘要:Axial anomeric sulfoxides generated via thiophenol Ferrier rearrangement of glucal and galactal derivatives are used to synthesize glycals of the gulal and allal series. An application of the method led to the synthesis of the esperamicin thiosugar.