CAS: 5696-15-1; 2-(Tert-Butylamino)-1-(2,5-Dimethoxyphenyl)Propan-1-Ol,Hydrochloride

专利信息

专利号:US-8815883-B2
优先权日:2009-11-02
标 题 :Compounds and methods for inhibiting serotonin synthesis
发明人：LANDRY DONALD; DENG SHI-XIAN
权利人:LANDRY DONALD; DENG SHI-XIAN; TRUSTEES OF COLUMBIA UNVIERSITY IN THE CITY OF NEW YORK
摘要:Compounds having the structures below that are TPH1 inhibitors are provided: The compounds are useful of, e.g., to increase bone mass. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis.

专利号:US-7888116-B2
优先权日:2004-07-22
标 题 :Uses of notch receptors, notch ligands, and notch modulators in methods related to metabolic diseases
发明人：EGAN JOSEPHINE M; DOYLE MAIRE E
权利人:US HEALTH
摘要:Disclosed are methods for identifying and isolating a precursor cell. Also, disclosed are methods of increasing insulin synthesis from a pancreatic B-cell. Further, disclosed are methods of improving pancreatic B-cell function. Still further, disclosed are methods of preventing or delaying the onset of a metabolic disease, methods of treating or preventing a metabolic disease in a subject, and to compositions for treating or preventing a metabolic disease in a subject in need of such treatment or prevention.

专利号:CN-101486668-B
优先权日:2003-12-30
标题 :Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof

专利号:WO-2014063189-A1
优先权日:2012-10-23
标题 :Methods and products for preventing and/or treating a stress induced cardiomyopathy
发明人：HOROWITZ JOHN; CHIRKOV YULIY
权利人:ADELAIDE RES & INNOVATION PTY
摘要:The present disclosure relates to methods and products for preventing and/or treating a stress- induced cardiomyopathy. Certain embodiments of the present disclosure provide a method of preventing and/or treating a stress-induced cardiomyopathy in a subject, the method comprising administering to the subject a therapeutically effective amount of one or more of the following agents: a peroxynitrite inhibitor; an inhibitor of peroxynitrite synthesis; an inhibitor of peroxynitrite associated signalling; an inhibitor of peroxynitrite-induced DNA damage; a Tx NIP inhibitor; a beta 2 adrenoceptor antagonist; and a beta 3 adrenoceptor antagonist; thereby preventing and/or treating the stress-induced cardiomyopathy in the subject.

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.