CAS: 462-39-5; 1,3-Difluoropropane

上下游产品

1,3-dibromo-propane trimethyleneglycol ethylene glycol propane 1,3-bis(di-tert-butylphosphino)propane 1,3-bis(dicyclohexylphosphine)propane

📜1,3-二溴丙烷置于potassium Fluoride体系中,化学反应生成 1,3-二氟丙烷
参考文献:F(Ch2)Nf (N=3-6) 分子构象的红外和拉曼光谱研究
标题:F(Ch2)Nf (N=3-6) 分子构象的红外和拉曼光谱研究
摘要:F(Ch2)Nf(N=3-6)的红外光谱和拉曼光谱在正常坐标处理的基础上进行了测量和分析.光谱分析表明,固态分子在n=3时采用gauche-Gauche构象,N=4时为gauche-Trans-Gauche',N=5时为gauche-Trans-Trans-Gauche,N=5时为gauche-Trans-Gauche构象. Trans-Trans-Gauche' 为 N=6.
DOI:10.1246/cl.1982.951

专利信息

专利号:US-11629137-B2
优先权日:2017-04-24
标 题:Methods of manufacturing of niraparib
发明人：STEWART ALISTAIR; TOTO ANTHONY JOSEPH; CHEN FRANK XING; WU GEORGE
权利人:TESARO INC
摘要:Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib.

专利号:WO-2024088910-A1
优先权日:2022-10-24
标 题 :Process for the preparation of a gadolinium contrast agent
发明人：HOG DANIEL; LONGERICH MARKUS; JACOBS TIA; GRUBE STEFAN; PLATZEK JONANNES; TERWILLIGER DANIEL WILLIAM; EBHARDT LASSE; BOEDDINGHAUS NICOLE; KUNELLIS JAN-CHRISTIAN; ULFERTS-HÄNEL ANITA; BALZER SANDRA; SCHIRMER HEIKO
权利人:BAYER AG
摘要:The present invention relates to a process for the preparation of a gadolinium chelate compound of formula (I) or its stereoisomers, tautomers, N-oxides, hydrates, solvates, or salts thereof, or mixtures of same. Further, the present invention relates to crystalline forms of the gadolinium chelate of formula (I), to a process for the preparation of said crystalline forms as well as to intermediate compounds in the synthesis of the gadolinium chelate compound of formula (I) and/or its crystalline forms as well as their stereoisomers, tautomers, N-oxides, hydrates, solvates, or salts thereof, or mixtures of same.

专利号:US-7994346-B2
优先权日:2001-11-06
标题 :Intermediates for the preparation of lipoxin A4 analogs
发明人：GROSSBACH DANJA; GUILFORD WILLIAM; SANDER MICHAEL
权利人:BAYER SCHERING PHARMA AG
摘要:This invention is directed to compounds useful as intermediates in the synthesis of lipoxin A 4 analogs of the following formulas (I) and (II): n nwherein R 1 , R 2 , R 3 , R 4 and R 5 are described herein. These analogs are useful in treating inflammatory and autoimmune disorders in humans. These analogs are also useful in treating pulmonary or respiratory tract inflammation in humans.

专利号:US-10611739-B2
优先权日:2016-08-16
标题:Process for preparation of lactone derivatives and intermediates thereof
发明人：CHEN PING; PENG SHAOPING; LI YINQIANG; LI DAFENG; DONG XUEJUN
权利人:PHARMARESOURCES SHANGHAI CO LTD
摘要:A novel process for the preparation of lactone derivatives, and intermediates thereof is described. The lactone derivatives are important precursors for the synthesis of anti-hepatitis C virus agents, including sofosbuvir.

专利号:US-2023158469-A1
优先权日:2021-11-01
标题 :Devices and methods for synthesis
发明人：LACKEY JEREMY; DODD DAVID; PITSCH STEFAN
权利人:TWIST BIOSCIENCE CORP
摘要:Provided herein are compositions, devices, systems and methods for DNA oligomer synthesis. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.). The compositions, devices, systems and methods described herein provide improved synthesis, storage, density, and retrieval of biomolecule-based information.

专利号:US-2022402908-A1
优先权日:2019-07-08
标题 :Cxcr6 inhibitors and methods of use
发明人：PEDDIBHOTLA SATYAMAHESHWAR; HERSHBERGER PAUL M; KIRBY RICHARD JASON; MALANY SIOBHAN; SMITH LAYTON H; MALONEY PATRICK R; SESSIONS HAMPTON; DIVLIANSKA DANIELA; PINKERTON ANTHONY B
权利人:SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST
摘要:Provided herein are small molecule inhibitors of CXCR6 receptor, compositions comprising the compounds, and methods of using the compounds and compositions. The compounds are 9-azbicyclo[3.3.1]nonane or 9-diazbicyclo[3.3.1]nonane derivatives, whose synthesis is also described. Also provided are method of treating a disease or condition (such as, cancer) mediated by CXCR6/CXCL16 signaling pathway in a mammal.