CAS: 372-47-4; 3-Fluoropyridine

• 英文名称3-Fluoropyridine
• 中文名称3-氟吡啶
• IUPAC名称3-fluoropyridine
• 其它别名3-Fluoropyridine
• CAS编号372-47-4
• MFCD编号:MFCD00006374
• EINECS号:206-755-4
• FDA UNII编号:AP9KGY2VWZ
• 分子式:C5H4FN
• 分子量:97.09
• 产品CID: 1382414
• 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物

• 相似结构搜索
• InChIKey: CELKOWQJPVJKIL-UHFFFAOYSA-N
• InChI=1S/C5H4FN/c6-5-2-1-3-7-4-5/h1-4H…
• 计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数0.0

相似化合物

物理性质

• 熔点251-254 °C (分解)
• 沸点107°C at 760 mmHg
• 闪点13°C
• 密度1.1±0.1 g/cm3
• pKa:pK1:2.97(＋1) (25°C)
• PSA:12.89
• LogP:1.2207
• 折射率1.472
• 蒸汽压31.6±0.1 mmHg at 25°C
• 外观形态透明黄色液体
• 储存条件惰性气氛,室温
• 产品应用该化合物用于合成3-卤杀螨酯-4-YL-BORONIC酸和酯.
• 性质描述无色透明液体.沸点106-108°C,密度1.129,折光率1.472,闪点13°C.

MSDS等安全信息

• GHS象形图
• GHS符号GHS02 & GHS07;
  注释: Flame & Exclamation mark
• 危险类别易燃液体 类别2
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  严重眼刺激 类别2A
  急性毒性 类别4(吸入)
  急性毒性 类别4(经皮)
  急性毒性 类别4(经口)
• 警示词Danger(危险)
• 危险描述H225 |高度易燃液体和蒸气.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H332 |吸入有害.
  H312 |皮肤接触有害.
  H302 |吞咽有害.
• 防范说明P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501
• 危险等级3
• UN编号1993.0
• 危险品标志F,Xi,Xn
• 风险等级Flammable/Irritant
• 包装等级Ⅱ
• 安全声明16-26-36/37/39-33-7/9
• 危险类别码11-36/37/38-20/21/22
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 3-Fluoropyridine 主要起始原料 2,3,5,6-Tetrafluoropyridine
• 700-16-3 = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C2.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142]
  
  6485-79-6 = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Solvents: Toluene-D8; 2 H,Rt2.1 Solvents: Toluene; 3 D,Rt3.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142]
  
  617-86-7 = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Solvents: Toluene-D8; -30 °C; 20 H,-15 °C2.1 Solvents: Toluene-D8; 2 H,Rt3.1 Solvents: Toluene; 3 D,Rt4.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142]
  
  6485-79-6 = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Solvents: Toluene-D8; -30 °C; 20 H,-15 °C2.1 Solvents: Toluene-D8; 8 H,Rt -> 50 °C3.1 Solvents: Toluene; 3 D,Rt4.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142]
  
  2875-18-5 = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142]
  
  700-16-3 + 99476-19-4 = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Solvents: Toluene; 3 D,Rt2.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142]
  
  = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Solvents: Toluene-D8; 8 H,Rt -> 50 °C2.1 Solvents: Toluene; 3 D,Rt3.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142]
  
  = 372-47-4 + 76469-41-5 + 71902-33-5 + 3512-18-3 + 84476-99-3
  反应条件:1.1 Solvents: Toluene-D8; 8 H,Rt -> 50 °C2.1 Solvents: Toluene; 3 D,Rt3.1 Reagents: Triethylsilane Catalysts: Di-μ-Hydrobis[1,1′-(1,3-Propanediyl)Bis[1,1-Bis(1-Methylethyl)Phosphine-Kp]]Dirh... Solvents: Benzene-D6; 48 H,Rt -> 50 °C
  标题:Catalytic Hydrodefluorination Of Fluoroaromatics With Silanes As Hydrogen Source At A Binuclear Rhodium Complex: Characterization Of Key Intermediates
  作者:Zamostna,Lada; Et Al
  参考文献:Journal Of Fluorine Chemistry 日期:2013 卷标:155 页码:132-142

海关参考信息

• 2933310010-吡啶
  2939800000-其他生物碱
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管