CAS: 35023-55-3; (S)-Methyl 2-(Methylamino)Propanoate

相似化合物

20045-77-6 28819-05-8 28875-17-4

上下游产品

CAS号610800-48-1 N-methyl-N-4-ni... | CAS号24164-72-5 Z-L-MeAlaOMe | CAS号67-56-1 甲醇 | CAS号3913-67-5 N-甲基-L-丙氨酸 | CAS号27646-78-2 2-(甲基氨基)-1-丙醇

📜Z-L-Mealaome置于氢溴酸体系中,化学反应生成 N-甲基-L-丙氨酸甲酯盐酸盐
参考文献:使用氢化钠/甲基碘从氨基酸衍生物合成n-甲基氨基酸衍生物
标题:使用氢化钠/甲基碘从氨基酸衍生物合成n-甲基氨基酸衍生物
摘要:脂肪族氨基酸的 N-乙酰基-,N-苯甲酰基-和 N-羧基苯甲氧基衍生物与氢化钠/碘甲烷在含有二甲基甲酰胺的四氢呋喃中于 80°反应,以高产率得到相应的 N-甲基氨基酸甲酯,为油状.这些的皂化得到n-保护的-N-甲基氨基酸,脱羧基化得到n-甲基氨基酸甲酯氢硼化物.产品基本上是光学纯的,不含未甲基化的氨基酸衍生物.
DOI:10.1139/v71-317

专利信息

专利号:US-8735391-B2
优先权日:2008-09-26
标 题 :Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods
发明人：AUBE JEFFREY; ROTH BRYAN L; GHOSH PARTHA; FRANKOWSKI KEVIN J
权利人:AUBE JEFFREY; ROTH BRYAN L; GHOSH PARTHA; FRANKOWSKI KEVIN J; UNIV KANSAS
摘要:A functionalized polycyclic compound can have a structure of Formula 1 or salt, prodrug, analog, or derivative thereof, which compound can be prepared by providing a diene; reacting the diene with a dienophile under sufficient conditions for a combined Diels-Alder/acylation reaction so as to provide a polycyclic compound having a carboxylic acid; and coupling the carboxylic acid with an amine-containing compound or a hydroxyl-containing compound so as to form an amide or an ester and producing a compound having a structure of Formula 1. The compound can be used for modulating an opioid receptor, which can be conducted by administering to an opioid receptor a functionalized polycyclic compound as described herein in an effective amount to modulate the functionality of the opioid receptor. Such opioid modulation can provide a biological benefit to a subject.

专利号:US-2009275727-A1
优先权日:1998-03-24
标题:Peptide turn mimetics
发明人：CASSIDY PETER J; ALEWOOD PAUL FRANCIS; VERNALL ANDREA JOY
权利人:MIMETICA PTY LTD
摘要:This invention provides novel compounds useful for the synthesis of peptide mimetics, and describes the use of these compounds for the synthesis of novel reverse turn mimetics. The reverse turn mimetics of the invention have the general structure X wherein the variables are as defined herein.

专利号:US-2014243333-A1
优先权日:2008-09-26
标题:Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods

专利号:US-2010256142-A1
优先权日:2008-09-26
标 题 :Synthesis of functionalized octahydro-isoquinolin-1-one-8- carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods

专利号:US-2005032187-A1
优先权日:2003-08-01
标题:Novel peptide-forming enzyme, microbe producing the enzyme and method for producing peptide using them
发明人：YOKOZEKI KENZO; SUZUKI SONOKO; HARA SEIICHI; KATAYAMA SATOSHI
权利人:AJINOMOTO KK
摘要:The present invention relates to a novel enzyme that allows peptide to be produced easily, inexpensively and at high yield without going through a complex synthesis method. More particularly, the present invention provides a novel enzyme that catalyzes a peptide-producing reaction from a carboxy component and an amine component, a microbe that produces the enzyme, and a method for inexpensive production of peptides using this enzyme or microbe. The novel enzyme that efficiently produces peptide was discovered from a newly discovered microbe belonging to the genus Empedobacter , and a method was found that allows peptides to be produced inexpensively and easily.

专利号:US-2005032154-A1
优先权日:2002-07-26
标题 :Method for producing tripeptides and/or peptides longer than tripeptides
发明人：YOKOZEKI KENZO; SUZUKI SONOKO; HARA SEIICHI; ABE ISAO
权利人:AJINOMOTO KK
摘要:It is an object of the present invention to provide a method that allows the production of peptides that are equal to or longer than tripeptides easily, inexpensively and at high yield without going through a complex synthesis method. The inventors of the present invention have found a novel enzyme that efficiently produces a peptide from bacteria belonging to the genus Empedobacter or the genus Sphingobacterium . In the present invention, this enzyme is allowed to act on a carboxy component and an amine component to produce peptides that are equal to or longer than tripeptides.