CAS: 350-19-6; Ethyl 3,5-Difluorobenzoate

该化合物是一种氟芳烃酯,产自苯基环的3和5个位置,含有氟替代物,具有作为有机合成,特别是制药,农用化学品和特殊材料的多用途中间体的作用,这种化合物的价值在于它作为有机合成的多用途中间体的作用;氟原子的存在增强了它的活性和稳定性,使其在交叉反应和核循环替代中有用;其酯组在温和条件下可以进一步功能化;该化合物在普通有机溶剂中表现出良好的溶解性,便于其在实验室和工业应用中使用;在处理酸性或基本条件下对水解的潜在敏感性时,应当谨慎从事.

英文名称Ethyl 3,5-Difluorobenzoate
中文名称3,5-二氟苯甲酸乙酯
IUPAC名称ethyl 3,5-difluorobenzoate
其它别名Ethyl 3,5-Difluorobenzoate; Benzoic Acid, 3,5-Difluoro-, Ethyl Ester
CAS编号350-19-6
MFCD编号:MFCD03093801
EINECS号:252-319-1
分子式:C9H8F2O2
分子量:186.16
产品CID: 1355024
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: BLZSTFIKMISHNJ-UHFFFAOYSA-N
InChI=1S/C9H8F2O2/c1-2-13-9(12)6-3-7(10)5-8(11)4-6/h3-5H,2H2,1H3…
计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数2.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

上下游产品

3,5-diaminobenzoic acid ethyl ester ethanol 3,5-difluorobenzonitrile 3,5-difluorobenzoic acid3,5-difluorobenzoic acid ethyl 3,5-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 3-fluoro-5-(4-morpholinyl)benzoic acid 3-fluoro-5-morpholinobenzoyl chloride

合成工艺路线路线简述

合成目标产物 Ethyl 3,5-Difluorobenzoate 主要起始原料 Ethanol And 3,5-Difluorobenzoic Acid
(文献来源)合成步骤主要原料 Ethanol 和 3,5-Difluorobenzoic Acid

3,5-二氨基苯甲酸乙酯置于tetrafluoroboric Acid,Sodium Nitrite体系中,化学反应生成3,5-二氟苯甲酸乙酯
参考文献:The Preparation Of Some Fluoro-And Trifluoromethyl-Phenothiazines,And Some Observations Regarding Determination Of Their Structure By Infrared Spectroscopy1
标题:The Preparation Of Some Fluoro-And Trifluoromethyl-Phenothiazines,And Some Observations Regarding Determination Of Their Structure By Infrared Spectroscopy1
摘要:
Doi:10.1021/jo01128A018

海关参考信息

2906210000-苄醇
2912110000-甲醛
2912210000-苯甲醛
2915110000-甲酸
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-7993494-B2
优先权日:2008-01-23
标题:Method for manufacturing triarylpyrazine derivative
发明人：INOUE HIDEKO; NOMURA HIROKO
权利人:SEMICONDUCTOR ENERGY LAB
摘要:A novel synthesis method of a triarylpyrazine derivative, in particular, a manufacturing method by which a triarylpyrazine derivative, in specific, a 2,3,5-triarylpyrazine derivative in which an aryl group at a 5-position includes a substituent having an electron-withdrawing property can be synthesized with high yield as compared to a conventional method is provided. By using a synthesis method in which a mixture including a 1-aryl-2-(methylsulfinyl)ethanone derivative, meso-1,2-diarylethylenediamine, and a dehydrogenation agent is irradiated with a microwave to be reacted, the above object is achieved.

专利号:US-2012178931-A1
优先权日:2009-08-31
标题 :Process for preparation of pyrimidinylacetonitrile derivatives and intermediates for synthesis thereof

专利号:EP-2474536-B1
优先权日:2009-08-31
标题 :Process for preparation of pyrimidinylacetonitrile derivatives and intermediates for synthesis thereof
发明人：KAWAZOE KENTARO
权利人:IHARA CHEMICAL IND CO

专利号:EP-2474536-A1
优先权日:2009-08-31
标题 :Process for preparation of pyrimidinylacetonitrile derivatives and intermediates for synthesis thereof

专利号:CN-118791394-A
优先权日:2024-07-18
标题:Synthesis method of alpha-amino acid ester compound