专利号:US-5286901-A 优先权日:1990-03-09 标题:Prescursors for and synthesis of mono- and difunctionalized acetylenes and difunctional 1,3-diynes 发明人:STANG PETER J; CRITTELL CHARLES M; WILLIAMSON BOBBY L; ZHDANKIN VIKTOR 权利人:UNIV UTAH RES FOUND 摘要:Precursors and methods for the synthesis of mono- and difunctionalized acetylenes are described. The invention includes novel tricoordinate iodonium transfer reagents and novel alkynyldi(phenyliodonium) salts, both of which are precursors for the functionalized acetylenes. The iodonium transfer reagents take the general form of mixed iodonium sulfonates PhI + (X)OSO 2 R f , where X may be OAc, NHAc, NCO, or CN. These mixed iodonium sulfonates are produced by reaction of iodosobenzene with certain substituted trimethylsilanes. n To make the alkynyldi(phenyliodonium) salt PhI + C.tbd.CI + Ph•2 R f SO 3 - ,a mixed iodonium sulfonate is reacted with a bistin acetylene of the kind R' 3 SnC.tbd.CSnR' 3 . Alternatively, the reaction may be performed with disubstituted tin diacetylenes to produce PhI + C.tbd.C-C.tbd.CI + Ph•2 R f SO 3 - to produce a dialkynyldi(phenyliodonium) salt. Subsequent reaction of a nucleophile with the alkynyldi(phenyl-iodonium) salt or dialkynyldi(phenyliodonium) salt produces a difunctional acetylene or a difunctional 1,3-diyne, respectively.
专利号:US-7582758-B2 优先权日:2004-06-08 标 题:Lewis acid mediated synthesis of cyclic esters 发明人:MARTIN KEVIN V 权利人:METABASIS THERAPEUTICS INC 摘要:Methods for the synthesis of cyclic phosphonic acid diesters from 1,3-diols are described, whereby cyclic phosphonic acid diesters are produced by reacting a chiral 1,3-diol and an activated phosphonic acid in the presence of a Lewis acid.
专利号:US-5110970-A 优先权日:1991-03-29 标题 :Process for the manufacture of certain new silicone polyether copolymers for polyurethane foam manufacture 发明人:BLEVINS II CHARLES H; MATLOCK PAUL L; MURPHY GERALD J 权利人:UNION CARBIDE CHEM PLASTIC 摘要:This invention relates to silicone surfactants, and more particularly, to synthesis of siloxane-polyether surfactants having polyether backbones.
专利号:US-2022355262-A1 优先权日:2019-07-22 标题 :System and method for manufacturing water-based hydrophobic aerogels and aerogel composites 发明人:SACHITHANADAM MAHESH; KHORASGANI SOGHRATI ELMIRA; NATARAJAN GAYATHRI 权利人:KROSSLINKER PTE LTD 摘要:Embodiments of the present invention provide users with a system and method for manufacturing water-based hydrophobic aerogels and aerogel composites. The system and method can be carried out in a manner which is more rapid than typical ways and can be readily scalable. The method of manufacture is useful for producing water based hydrophobic aerogels and aerogel composites on a large scale with good homogeneity and consistency. Advantageously, the method of manufacture also has the benefit of a shorter processing time due to the vacuum homogenizing and mixing processes, the use of microwave assisted vacuum freeze drying for ease of synthesis of water-based hydrophobic aerogels.
专利号:US-6160128-A 优先权日:1997-12-22 标题:Tritioacetylating reagents and processes for preparation thereof 发明人:SALJOUGHIAN MANOUCHEHR; MORIMOTO HIROMI; WILLIAMS PHILIP G; THAN CHIT 权利人:UNIV CALIFORNIA 摘要:Novel acetylating and tritioacetylating reagents suitable for preparation of nonlabelled and radiolabelled organic compounds. N-acetoxynaphthalimide, N-tritioacetoxyphthalimide, N-tritioacetoxysuccinimide, N-tritioacetoxynaphthalimide and processes of their preparation. The invention also concerns synthesis of nonlabelled acetylated and tritioacetylated organic compounds from precursors containing a free --NH 2 , --SH or --OH group.
专利号:US-7598408-B2 优先权日:2003-02-25 标 题:Intermediates for synthesis of vitamin D derivatives 发明人:IMAHORI HIDEKAZU; KOYAMA HIROYA; YOSHIHARA DAISUKE; SAWASHITA YOSHINORI; KURITA SOTA; ICHIHARA YOSHIHIRO; TAKAGI YOSHIHIRO; HIROSE KATSUTOSHI 权利人:KNC LAB CO LTD 摘要:The present invention provides a novel intermediate for synthesizing vitamin D derivatives by using a less expensive material. That is, the present invention provides a compound which is synthesized by using carvone as a starting material and which is represented by the following formulae.
摘要:Petasis, N. A., Science of Synthesis, (2010) 47, 232. 摘要:Zhdankin, V. V., Science of Synthesis Knowledge Updates, (2015) 1, 272. 摘要:Witt, D., Science of Synthesis Knowledge Updates, (2019) 2, 293. 摘要:Martínez, C.; Muñiz, K., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 329.