CAS: 115-53-7; Sinomenine

上下游产品

CAS号22610-64-6 4-acetyl-sinomenine

(4Br,8As,9S)-3,7-Dimethoxy-11-Methyl-6-Oxo-6,8A,9,10-Tetrahydro-5H-9,4B-(Epiminoethano)Phenanthren-4-Yl Propionate置于甲基三辛基氯化铵,Potassium Hydroxide体系中,用 水 用作溶剂,化学反应 2.0H,以99%的收率获得青藤碱
参考文献:水不溶性高熔点有机底物水反应的实用解决方案
标题:水不溶性高熔点有机底物水反应的实用解决方案
摘要:对于难溶性高熔点(vsshmp)有机底物进行水反应的问题,已经开发出一种实用的解决方案,该方法需要机械搅拌底物,相应的试剂,水,催化性aliquat 336的混合物和沙子.当包括类固醇,酮,醛,芳族化合物和生物碱的底物的熔点为约200oc时,反应可以在20oc下进行.底物溶解度可以低至1x10-10 Mol L-1.
Doi:10.1039/c2Gc16328D

专利信息

专利号:US-8252928-B2
优先权日:2008-09-16
标题:Processes for the synthesis of five and six membered heterocyclic rings
发明人：WANG PETER X; JIANG TAO; BERBERICH DAVID W
权利人:WANG PETER X; JIANG TAO; BERBERICH DAVID W; MALLINCKRODT LLC
摘要:The present invention provides processes for the synthesis of five and six membered rings. In particular, the present invention provides processes for the synthesis of five and six membered rings in alkaloids.

专利号:US-8614224-B2
优先权日:2007-12-17
标 题 :Sinomenine derivatives and processes for their synthesis
发明人：WANG PETER X; JIANG TAO; CANTRELL GARY L; BERBERICH DAVID W; TRAWICK BOBBY N; LIAO SUBO; BRANDT JOHN
权利人:WANG PETER X; JIANG TAO; CANTRELL GARY L; BERBERICH DAVID W; TRAWICK BOBBY N; LIAO SUBO; BRANDT JOHN; MALLINCKRODT LLC
摘要:The invention generally provides processes and intermediate compounds useful for the production of sinomenine derivatives. In particular, the process may encompass synthetic routes for the production of (+)-sinomenine derivatives and their intermediates.

专利号:ES-2664252-T3
优先权日:2008-09-16
标 题:Processes for the synthesis of five- and six-membered heterocyclic rings

专利号:CA-2737159-C
优先权日:2008-09-16
标 题:Processes for the synthesis of five and six membered heterocyclic rings

专利号:WO-2010033442-A1
优先权日:2008-09-16
标 题 :Processes for the synthesis of five and six membered heterocyclic rings

专利号:EP-2328899-B1
优先权日:2008-09-16
标 题 :Processes for the synthesis of five and six membered heterocyclic rings