CAS: 105151-39-1; Diethyl 5-Ethylpyridine-2,3-Dicarboxylate

相似化合物

102268-15-5 2050-22-8 105151-48-2

上下游产品

CAS号922-63-4 2-乙基丙烯醛 | CAS号34034-87-2 氯代草酰乙酸二乙酯 | CAS号133093-91-1 diethyl 2-amino... | CAS号36016-13-4 diethyl 1-amino... | CAS号1629-58-9 1-戊烯-3-酮 | CAS号141-05-9 顺丁烯二甲酸二乙酯 | CAS号108-56-5 草酰乙酸二乙酯 | CAS号86319-87-1 diethyl 2-amino... | CAS号142-96-1 正丁醚 | CAS号105-39-5 氯乙酸乙酯 | CAS号81335-77-5 咪草烟 | CAS号102268-15-5 5-乙基吡啶-2,3-二羧酸

草酰乙酸二乙酯置于钯 乙酸铵,汞体系中,用 甲苯 用作溶剂,以34.7 Wt. %的收率获得5-乙基吡啶-2,3-二羧酸二乙酯
参考文献:Process For Preparing Pyridine Carboxylic Acid Esters
标题:Process For Preparing Pyridine Carboxylic Acid Esters
摘要:本发明公开了一种通过将酮酯(如二甲基草酸乙酯)与α,β-不饱和醛或酮(如2-乙基丙烯醛)以及至少1摩尔当量的铵盐在合适溶剂中反应,利用钯载碳作为脱氢催化剂来制备2,3-吡啶二羧酸酯的新方法.

专利信息

专利号:US-5101067-A
优先权日:1988-12-01
标 题:2-amino-3-halomaleic acid esters
发明人：MEIER JOSEF; DEINHAMMER WOLFGANG; KRAGELOH KONRAD
权利人:WACKER CHEMIE GMBH
摘要:The invention relates to a process for the preparation of pyridine-2,3-dicarboxylic acid esters using novel maleic acid esters as starting materials. In the process, in a first process step, 2,3-dihalomaleic acid esters are reacted with ammonia, or ammonium salts, with the exclusion of water at a temperature of at least 50°0 C. to form novel 2-amino-3-halomaleic acid esters, and these are subsequently reacted further in a second process step with α,β-unsaturated aldehydes, or ketones, in the presence of an acidic catalyst and acid-binding agents at a temperature of at least 50° C. with heat being supplied until the pyridine-2,3-dicarboxylic acid esters have been formed. Pyridine-2,3-dicarboxylic acid esters of this type can be used for example, as intermediates for synthesis of herbicides based on imidazoline. The present invention also relates to novel 2-amino-3-halomaleic acid esters, which are useful for producing the final product pyyridine-2,3-dicarboxylic acid esters.

专利号:CN-103524485-A
优先权日:2013-09-10
标题:A method for continuous synthesis of imazethapyr

专利号:CN-115403518-A
优先权日:2022-09-19
标题 :Continuous flow synthesis process of 5-alkylpyridine-2, 3-dicarboxylic ester

专利号:CN-103524485-B
优先权日:2013-09-10
标题:A kind of method of serialization synthesis imazethapyr

专利号:CN-112142728-B
优先权日:2019-06-28
标题 :A kind of imazethapyr intermediate and its synthesis method and application

专利号:CN-115403518-B
优先权日:2022-09-19
标 题:Continuous flow synthesis process of 5-alkylpyridine-2, 3-dicarboxylic acid ester