CAS: 642-83-1; Aceglatone

该化合物是化学化合物,主要因其在药物应用中的作用而得到承认,特别是作为抗糖尿病剂,被归类为磺酰胺,这意味着它通过刺激胰腺的胰岛素分泌发挥作用,从而帮助降低2型糖尿病人的血液甘蔗含量;该化合物的特点是它能够提高外围组织对胰岛素的敏感性,有助于改进葡萄糖的吸收;甲状腺素一般是口服的,并因其相对快速的开始作用而闻名;就其化学结构而言,它包含一个磺酰胺组,是其行动机制的组成部分;该化合物一般都是经过良好调试的,尽管它与许多药物一样,也可能具有副作用,包括低血糖和胃肠紊乱,其功效和安全特征使它在糖尿病的管理中成为有价值的选择,尽管对于病人来说,在医疗监督下使用它是至关重要的.

结构式图片

MSDS等安全信息

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于硫酸,乙酸酐,乙酰氯体系中,化学反应生成 醋葡醛内酯
    参考文献:Valentin,Collection Of Czechoslovak Chemical Communications,1937,Vol. 9,P. 315,322
    标题:Valentin,Collection Of Czechoslovak Chemical Communications,1937,Vol. 9,P. 315,322

    海关参考信息

    专利信息


    专利号:WO-2023008461-A1
    优先权日:2021-07-27
    标题:Medicament for treatment and/or prevention of cancer
    发明人:KUME MASAHIKO; OKANO FUMIYOSHI; SAITO TAKANORI
    权利人:TORAY INDUSTRIES
    摘要:The present invention relates to a medicament for the treatment and/or prevention of cancer, the medicament being characterized by comprising an antibody having an immunological reactivity with CAPRIN-1 protein or a fragment of the antibody and a drug capable of inhibiting the N-glycoside-linked sugar chain synthesis of a glycoprotein which are combined with each other in a blended or separated form.

    专利号:US-4975441-A
    优先权日:1988-03-23
    标 题:Lactams, their synthesis and use in cosmetic compositions
    发明人:GIBSON WALTER T
    权利人:UNILEVER PATENT HOLDINGS
    摘要:A composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises: (i) a chemical inhibitor of glycosidase activity chosen from lactams having the structure: where A<1> and A<6> are -H, -CH3, - @@0, -CH2OT or @@@0 A<1> and A<6> being the same or different, and at least one of which being the group: @ @@o in a lactam ring; and where Q is -OT min , -NHT min or a lactam linkage to A<1> or A<6>; the Q groups being the same or different, and at least one of which is involved in a lactam linkage; and where T is the same or different and is chosen from -H, -CpH2p+1 or a metal ion, T min is -H or -COCpH2p+1, and p is an integer of from 1 to 22; provided that: where any of the Q groups is -OT min or -NHT min , then that group or groups can be of either stereochemical configuration with respect to the plane of the ring; and (ii) a cosmetically acceptable vehicle for the chemical inhibitor. Certain novel lactams are also claimed.

    专利号:KR-20090077942-A
    优先权日:2006-10-05
    标题:Effective synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:RU-2512491-C2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and use

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1124/mol.119.115964
    摘要:Lee TD, Lee OW, Brimacombe KR, Chen L, Guha R, Lusvarghi S, Tebase BG, Klumpp-Thomas C, Robey RW, Ambudkar SV, Shen M, Gottesman MM, Hall MD. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology. 2019 Nov;96(5):629–40. doi: 10.1124/mol.119.115964.
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