CAS: 6320-01-0; 3-Bromothiophenol

上下游产品

3-Bromobenzenesulfonyl chloride m-Bromoaniline [(3-bromophenyl)sulfanyl]acetic acid potassium ethyl xanthogenate 2-(3-bromo-phenylsulfanyl)-5-nitro-pyridine [(3-bromophenyl)sulfanyl]acetic acid 3-bromo-1-(methylthio)benzene 1-bromo-3-[(3-bromophenyl)disulfanyl]benzene

3-溴苯磺酰氯置于硫酸,锌体系中,化学反应生成 3-溴苯硫酚
参考文献:具有药理活性的苯并[B]噻吩衍生物.第六部分 N-2-氯乙基-N-乙基-3-氨基甲基苯并[B]噻吩盐酸盐的4-和6-卤代衍生物
标题:具有药理活性的苯并[B]噻吩衍生物.第六部分 N-2-氯乙基-N-乙基-3-氨基甲基苯并[B]噻吩盐酸盐的4-和6-卤代衍生物
摘要:(环化米热多磷酸-Chlorophenylthio)丙酮,得到的混合物中4-氯和6-氯-3-甲基苯并[B]噻吩(7:4),和(米-Bromophenylthio)丙酮4:1的混合物-溴和6-溴-3-甲基苯并[B]噻吩(1:3).这些产物通过4-和6-氯-3-甲基苯并[B]噻吩和4-溴-3-甲基苯并[B]噻吩的明确合成来鉴定.n取代溴代3-甲基苯并[B]噻吩在沸腾的四氯化碳中的-溴代琥珀酰亚胺得到相应的溴甲基化合物,该化合物容易与2-乙基氨基乙醇在沸腾的苯中反应.所得的氨基醇与亚硫酰氯在干沸腾的氯仿中反应,得到所需的(2-氯乙基)胺.
DOI:10.1039/j39680002747

专利信息

专利号:WO-2021083438-A1
优先权日:2019-10-30
标 题:Inhibitors of purine nucleoside phosphorylase - synthesis and use thereof for treatment of t-cell acute lymphoblastic leukemia and lymphoma
发明人：SKACEL JAN; JANEBA ZLATKO; MERTLIKOVA KAISEROVA HELENA
权利人:USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I
摘要:The present invention relates to new compounds of general formula I, their synthesis, their pharmaceutically acceptable salts, and their use in treatment of T-cell acute lymphoblastic leukemia and lymphoma.

专利号:US-2010137244-A1
优先权日:2006-07-13
标题 :Preparation and utility of hmg-coa reductase inhibitors
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:Chemical syntheses and medical uses of novel modulators of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and diastereomeric mixtures of isomers, individual diastereomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of hypercholesterolemia, dyslipidemia, coronary artery disease, atherosclerosis, metabolic syndrome, a hyperproliferative disease such as colorectal cancer, prostate cancer, and melanoma, a neurodegenerative disease such as cerebral ischemia, Alzheimer's disease, and Parkinson's disease are described.

专利号:US-12227528-B2
优先权日:2017-11-09
标 题:Glucose-sensitive albumin-binding derivatives
发明人：KRUSE THOMAS; KOFOD-HANSEN MIKAEL; MUENZEL MARTIN WERNER BORCHSENIUS; THOEGERSEN HENNING; SAUERBERG PER; EWALD JAKOB; BEHRENS CARSTEN; HOEG-JENSEN THOMAS; BALSANEK VOJTECH; DROBNAKOVA ZUZANA; DROZ LADISLAV; HAVRANEK MIROSLAV; KOTEK VLADISLAV; STENGL MILAN; SNAJDR IVAN; DRUSANOVA HANA
权利人:NOVO NORDISK AS
摘要:This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.

专利号:GB-1582960-A
优先权日:1976-07-01
标题:Chemical synthesis of -lactam derivatives

专利号:CN-109402659-A
优先权日:2018-12-28
标题 :A kind of green synthesis method of α-thioenamine compound

专利号:US-8557837-B2
优先权日:2010-02-10
标题:Sinomenine derivatives, synthetic methods and uses thereof
发明人：YAO ZHUJUN; SUN BING; LOU YANGTONG; YANG ZHENYU; CHEN AIZHONG; MA ZHAO
权利人:YAO ZHUJUN; SUN BING; LOU YANGTONG; YANG ZHENYU; CHEN AIZHONG; MA ZHAO; SHANGHAI INST ORGANIC CHEM; SHANGHAI INST BIOL SCIENCES
摘要:The invention relates to sinomenine derivatives, methods for their synthesis and their applications. The sinomenine derivatives include oxidation derivatives, and C-10 substituted sinomenine derivatives. Based on the readily oxidizable phenol group on sinomenine structure, using oxidation, oxidative dearomatization, or conjugated addition aromatization, one can introduce C-10 substitutions to synthesize the sinomenine derivatives. The sinomenine derivatives of the invention have the following structures: n n n n n n n n n n Using in vitro TNF-α inhibition assay, the activities of the synthetic compounds are assessed. Results from these assays shown that most compounds have anti-inflammatory effects, and some compounds have better activities than that of sinomenine. These compounds may be used in treating immune diseases such as rheumatoid arthritis (RA).