CAS: 603-56-5; 5-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-3,6,7-Trimethoxy-4H-Chromen-4-One

该化合物是主要来自各种植物来源的氟氯素化合物,特别是阿斯特拉夏家族的植物来源,其特征是黄色晶状外观,以其抗氧化特性而著称,有助于其潜在的健康利益. 氯氟化碳展示了一系列生物活动,包括抗炎和抗微生物影响,使其对药理研究感兴趣.该化合物的结构具有氟香骨干,这是许多氟氯素的典型特征,并拥有增强其在极溶剂中的再活性和溶解性的氢氧基.此外,还研究了丙烯基苯在保护细胞免受氧化压力方面的潜在作用,并可能对治疗剂的发展产生影响. 它存在于各种植物中,也表明其在传统医学中的作用,尽管需要进一步研究以充分了解其机制和应用.

结构式图片

上下游产品

CAS号90-18-6 槲皮万寿菊素

合成工艺路线路线简述

    2-(4-Hydroxy-3-Methoxy-Phenyl)-3,5,6,7-Tetramethoxy-Chromen-4-One 反应生成 猫眼草黄素
    参考文献:Horie,Tokunaru;Kawamura,Yasuhiko;Tsukayama,Masao;Yoshizaki,Shiro,Chem. And Pharm. Bull.,37,(1989) N,C. 1216-1220
    标题:Horie,Tokunaru;Kawamura,Yasuhiko;Tsukayama,Masao;Yoshizaki,Shiro,Chem. And Pharm. Bull.,37,(1989) N,C. 1216-1220

    海关参考信息

    专利信息


    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.
    成都格纯生物医药有限公司
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    主要参考文献


    1: Cao C, Liu B, Shen W, Wang H, Li Y. [Research on antiproliferative effect of flavones isolated from Laggera pterodonta]. Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(16):2171-4. Chinese. 5(46):29755-29764. doi: 10.1021/acsomega.0c03582.
    4: Lu P, Wu JM, Chen LJ, Li W. [Chemical constituents from Laggera pterodonta]. Zhong Yao Cai. 2014 May;37(5):816-9. Chinese. 35(5):602-6. Chinese. doi: 10.4268/cjcmm20100513. 42(5):511-5. 16(5):289-90, 318. Chinese. 31(21):1790-2. Chinese.

    合成参考文献


    参考文献:10.1016/j.toxlet.2018.05.008
    摘要:Li Y, Ning J, Wang Y, Wang C, Sun C, Huo X, Yu Z, Feng L, Zhang B, Tian X, Ma X. Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. Toxicol Lett. 2018 Sep 15;294():27–36. doi: 10.1016/j.toxlet.2018.05.008.
    参考文献:10.3390/v11070625
    摘要:Dai W, Bi J, Li F, Wang S, Huang X, Meng X, Sun B, Wang D, Kong W, Jiang C, Su W. Antiviral Efficacy of Flavonoids against Enterovirus 71 Infection in Vitro and in Newborn Mice. Viruses. 2019 Jul 07;11(7).
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