CAS: 5445-19-2; Methyl 2-Bromohexanoate

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868-73-5 41796-82-1 616-05-7

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CAS号13894-63-8 反式-2-己烯甲酯 | CAS号616-05-7 2-溴己酸 | CAS号67-56-1 甲醇 | CAS号91423-84-6 Hexanoic acid, ... | CAS号186581-53-3 重氮甲烷 | CAS号141645-51-4 2-丁基-5-苯并呋喃胺 | CAS号4265-27-4 2-丁基苯并呋喃 | CAS号141626-36-0 决奈达隆 | CAS号158745-55-2 2-phenoxyhexanal | CAS号133238-87-6 2-丁基-5-硝基苯并呋喃 | CAS号335153-21-4 2-(2-甲酰基-4-硝基苯氧基)正己酸 | CAS号335153-23-6 Methyl 2-(2-for... | CAS号138320-27-1 2-(2-formylphen... | CAS号138320-26-0 2-(2-甲酰基苯氧基)己酸甲酯 | CAS号81629-62-1 methyl 2-azidoh...

己酸甲酯置于正丁基锂,二异丙胺,N-溴代丁二酰亚胺(Nbs)体系中,用 四氢呋喃,正己烷 作为反应溶剂,化学反应 0.58H,以51%的收率获得产物2-溴己酸甲酯
参考文献:使用 N-溴酰胺和可见光进行位点选择性脂肪族 C-H 溴化
标题:使用 N-溴酰胺和可见光进行位点选择性脂肪族 C-H 溴化
摘要:选择性功能化脂肪族 Ch 键的转化有望简化复杂分子的合成.尽管具有位点选择性 Ch 功能化的潜力,但很少有具有制备价值的分子间过程.在此,我们报告了一种使用现成的 N-溴酰胺试剂和可见光进行未活化的脂肪族 Ch 溴化的方法.这些卤化以有用的化学产率进行,底物作为限制试剂.这些自由基介导的 Ch 官能化的位点选择性与已知的最具选择性的分子间 Ch 官能化相当(或优于).由于烷基溴作为合成中间体的广泛用途,这种方便的方法将普遍用于化学合成.
DOI:10.1021/ja508469U

专利信息

专利号:US-4234744-A
优先权日:1978-12-18
标 题 :Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides
发明人：EFFENBERGER FRANZ; DRAUZ KARLHEINZ
权利人:DEGUSSA
摘要:Aminoacid hydrochlorides or diaminoacid dihydrochlorides are produced by first reacting a halocarboxylic acid ester with an alkali metal cyanate in the presence of an alcohol to form the corresponding mono- or diurethane and then saponifying this to the corresponding mono- or dihydrochloride. The new process is relatively versatile in its use and above all opens up an elegant synthesis route for lysine.

专利号:US-7781470-B2
优先权日:1999-09-13
标题:Aminodicarboxylic acid derivatives having pharmaceutical properties
发明人：ALONSO-ALIJA CRISTINA; HEIL MARKUS; FLUBACHER DIETMAR; NAAB PAUL; PERNERSTORFER JOSEF; STASCH JOHANNES-PETER; WUNDER FRANK; DEMBOWSKY KLAUS; PERZBORN ELIZABETH; STAHL ELKE
权利人:BAYER SCHERING PHARMA AG
摘要:The invention relates to compounds of formulae (II), (IV), and (VI) as shown below, n nwherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for using them in the synthesis of compounds for treatment of cardiovascular disorders and fibrotic disorders are also disclosed.

专利号:CN-1858042-A
优先权日:2006-06-09
标 题:Synthesis of 2-butyl-3-(4-hydroxy-3,5-diiodobenzoyl)benzofuran

专利号:WO-0002864-A1
优先权日:1998-07-10
标题:Precusors for pna-monomers
发明人：MARTENS JUERGEN; MAISON WOLFGANG; SCHLEMMINGER IMRE; WESTERHOFF OLE; GROEGER HARALD
权利人:MARTENS JUERGEN; MAISON WOLFGANG; SCHLEMMINGER IMRE; WESTERHOFF OLE; GROEGER HARALD
摘要:The invention is directed to compounds of formula (I) wherein A, B, D, E, X and Y are defined in the description. These compounds are useful precursors for the synthesis of monomers for Peptide Nucleic Acids (PNA).

专利号:CN-102659726-B
优先权日:2012-03-30
标题:Method for synthesis of dronedarone