CAS: 531-81-7; 2-Oxo-2H-Chromene-3-Carboxylic Acid

上下游产品

pyridine malonic acid salicylaldehyde 3-cyan°Coumarinpropyl 2-oxo-2H-chromene-3-carboxylate butyl 2-oxo-2H-chromene-3-carboxylate coumarin 3-carboxylic acid chloride coumarin

📜2-(2-甲氧基亚苄基)丙二酸置于水体系中,化学反应 12.0H,反应生成 香豆素-3-羧酸
参考文献:A One-Pot Synthesis Of Coumarins From Dipotassium O-Methoxybenzylidenemalonates
标题:A One-Pot Synthesis Of Coumarins From Dipotassium O-Methoxybenzylidenemalonates
摘要:O-Methoxybenzylidenemalonates 1,Which Are Available From O-Methoxybenzaldehydes And Diethyl Malonate,Were Hydrolysed To The Dipotassium Malonates 2. Treatment Of The Salts 2 With Trifluoroacetic Acid-Trifluoroacetic Anhydride Gave The Title Coumarins By A Demethylative Ring-Closure Reaction In 60-80% Yield.
DOI:10.1039/p19910000219

专利信息

专利号:US-2021107859-A1
优先权日:2018-04-06
标题 :A process for the synthesis of carbon labeled organic compounds
发明人：AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.

专利号:WO-0120995-A9
优先权日:1999-09-23
标题:Compounds directed against pilus biogenesis and activity in pathogenic bacteria; methods and compositions for synthesis thereof
发明人：KIHLBERG JAN; LARSSON ANDREAS; SVENSSON ANETTE; FEX TOMAS; HULTGREN SCOTT J; PINKNER JERRY
权利人:UNIV WASHINGTON; KIHLBERG JAN; LARSSON ANDREAS; SVENSSON ANETTE; FEX TOMAS; HULTGREN SCOTT J; PINKNER JERRY
摘要:Many Gram-negative pathogens assemble adhesive structures on their surfaces that allow them to colonize host tissues and cause disease. Novel compositions which inhibit or prevent the formation of a pilus chaperone-subunit complex are disclosed. Interfering with the function of the pili chaperone negatively affects the chaperone/usher pathway which is one molecular mechanism by which Gram-negative bacteria assemble adhesive pili structures and thus prevent or inhibit pilus assembly. Also provided are methods for the treatment or prevention of diseases caused by tissue-adhering pilus-forming bacteria by inhibiting the function of pilus chaperones. Also provided are pharmaceutical preparations capable of inhibiting or preventing the formation of a pilus chaperone-subunit complex. Also provided are methods of synthesizing the N-substituted amino acid compounds and compounds useful for the synthesis thereof. In particular, novel fluorinated linker compounds and methods of synthesis are provided. Methods for using the fluorinated linker compounds in methods of solid-phase synthesis of the N-substituted amino acid compounds are also disclosed.

专利号:US-11938546-B2
优先权日:2018-10-18
标题:Precision control of large-scale green synthesis of biodegradable gold nanodandelions as potential radiotheranostics
发明人：LO LEU-WEI; CHUANG YAO-CHEN
权利人:NATIONAL HEALTH RES INST; LO LEU WEI
摘要:The present invention relates to a new type of metabolizable flower-like gold nanodandelion (GND), which possesses features: (1) large scale green synthesis with high monodispersity and a circa 100% yield; (2) cellular/physiological degradability; (3) precision control of the shape, petal number and size; (4) highly efficient radiotheranostics encompassing better enhanced CT contrast and pronounced x-ray induced ROS generation than conventional spherical AuNP.

专利号:US-6534637-B2
优先权日:2001-02-12
标 题 :Synthesis of chlorophenol red glucuronic acid
发明人：SHEN GENE G Y; OH CHAN S; YANCEY STEPHANIE D; ADAMS CRAIG W
权利人:BECKMAN COULTER INC
摘要:This invention provides beta-D-Glucuronidase substrates of the formula:whereinR1, R2, and R7-R12 are independently selected from the group consisting of:hydrogen, fluorine, chlorine, bromine, iodine, alkyl, hydroxyl, alkoxy, carboxyl and nitro groups;R3-R6 are independently selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, nitro and amino; andM+ is selected from the group consisting of: proton, lithium, sodium, potassium, magnesium, calcium, barium, and ammonium ion.

专利号:US-7183405-B2
优先权日:1999-06-25
标 题 :Compositions and methods for labeling oligonucleotides
发明人：CHIARELLO RONALD H; LIU WING-CHEONG; ALVARADO GABRIEL G
权利人:SYN GEN INC
摘要:A novel method for the labeling of oligonucleotides which results in the economical synthesis of 5′ labeled molecules. A set of suitably protected and carefully selected set of amino linkers, a modified deprotination/cleavage protocol and standard coupling methodologies to are used to allow for the convergent synthesis of any number of labeled oligonucleotides.

专利号:US-2023295613-A1
优先权日:2020-02-14
标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming
发明人：JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J
权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.