CAS: 482-15-5; N,N-Dimethyl-1-Pyrido[3,2-B][1,4]Benzothiazin-10-Ylpropan-2-Amine
该化合物是一种属于被称为硫代苯并二氮杂卓的化合物类别的抗口服胺,主要用于抗过敏性,有效缓解与过敏反应有关的症状,如干热和尿道等;异丁基功能,阻断H1受体的异丁胺行动,从而减少了异丁胺释放的生理影响;该化合物的特点是水溶性相对较低,影响其药用植物和生物利用率;通常通过口服施用,并具有中度行动期;在安全方面,它与许多抗口服胺一样,可能会产生副作用,如潮湿,干口服或眩晕等;此外,还必须考虑到与其他药物,特别是具有镇静剂效应的药物的潜在相互作用;
- 英文名称N,N-Dimethyl-1-Pyrido[3,2-B][1,4]Benzothiazin-10-Ylpropan-2-Amine
- 中文名称氮异丙嗪
- IUPAC名称N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine
- 其它别名10H-Pyrido[3,2-b][1,4]benzothiazine,10-[2-(dimethylamino)propyl]- (6CI,7CI,8CI); (?à)-Isothipendyl; 10-(2-Dimethylamino-2-methylethyl)-10H-pyrido[3,2-b][1,4]benzothiazine; 10-(2-Dimethylaminopropyl)-1-azaphenothiazine; 10-(2-Dimethylaminopropyl)-9-thia-1,10-diazaanthracene; 10-(2-Dimethylaminopropyl)thiophenylpyridylamine; 10-[2-(Dimethylamino)propyl]-10H-pyrido[3,2-b][1,4]benzothiazine; Dimethylaminoisopropylazaphenothiazine; Isothipendyl; N-Dimethylaminoisopropylthiophenylpyridylamine; Odantol; Udantol
- CAS编号482-15-5
- MFCD编号:MFCD00865664
- EINECS号:207-578-5
- FDA UNII编号:WVZ7K9P0JY
- 分子式:C16H19N3S分子量:285.41
- 产品CID: 1476816
- 同类组份化合物CAS482-15-5 (free base)1225-60-1 (HCl)
- 产品分类化学试剂 → 有机试剂 → 多环化合物
物理性质
MSDS等安全信息
欧盟法规
REACH注册ECHA物质C&L通报REACH预注册上下游产品
CAS号92316-06-8 2-[(3-硝基-2-吡啶)磺酰基]苯胺 | CAS号91902-18-0 N-[2-(3-nitropy... | CAS号137-07-5 2-氨基苯硫酚 | CAS号261-96-1 氮杂苯酚噻嗪 | CAS号108-14-5 2-氯-N,N-二甲基-1-丙胺 | CAS号6631-37-4 2-苯基氨基吡啶 | CAS号53309-35-6 2-二甲氨基氯丙烷合成工艺路线路线简述
📜1-(10H Benzo[b]Pyrido[2,3-E][1,4]Thiazin-10-yl)Ethane-1-One置于盐酸,Sodium Amide,Xylene体系中,化学反应生成 氮异丙嗪
参考文献:10-(Dialkylaminoalkyl)-Pyrido[3,2-B][1,4]Benzothiazine (1-Azaphenothiazine) And Related Compounds
标题:10-(Dialkylaminoalkyl)-Pyrido[3,2-B][1,4]Benzothiazine (1-Azaphenothiazine) And Related Compounds
摘要:
DOI:10.1021/ja01540A035
海关参考信息
- 2921211000-乙二胺
2933310010-吡啶
2930909099-其他有机硫化合物
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2003138490-A1
优先权日:2001-09-08
标 题 :Synthesis and uses of polymer gel nanoparticle networks
发明人：HU ZHIBING; LU XIHUA; GAO JUN; PONDER BILL C; JOHN JOHN ST; MORO DANIEL G
摘要:Disclosed is a new class of nanostructured polymeric materials comprising polymer gel nanoparticles that are covalently bonded through functional groups on the surfaces of neighboring particles. These nanoparticles may be prepared as suspensions in an aqueous or, non-aqueous environment. These gels have two unique and different structural networks; the primary network comprises crosslinked polymer chains in each individual particle, while the secondary network is a system of crosslinked nanoparticles. Particular polymer gel nanoparticle network compositions disclosed herein may function as carriers for controlled delivery of pharmaceuticals or other chemical agents, gel sensors and other commercial applications.
专利号:CN-102617608-A
优先权日:2012-03-09
标题 :A kind of synthesis and separation method of antihistamine azipromazine
专利号:WO-03022910-A1
优先权日:2001-09-08
标题:Synthesis and uses of polymer gel nanoparticle networks
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
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主要参考文献
1: Bibas N, Sartor V, Bulai Livideanu C, Bagheri H, Nougué J, Giordano-Labadie F, Maza A, Paul C, Chouini-Lalanne N, Marguery MC. Contact photoallergy to isothipendyl chlorhydrate. Dermatology. 2012;224(4):289-91. doi: 10.1159/000338024. Epub 2012 Jun 1. Japanese. Portuguese. Ann Allergy. 1958 May-Jun;16(3):237-41.
合成参考文献
摘要:Arzneimittel-Forschung. Drug Research., 8(489), 1958 []
摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
摘要:S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (2021) DOI:10.1021/acsenvironau.1c00008. List downloaded from
参考文献:10.1107/s1600536810021367
摘要:Arunkashi HK, Jeyaseelan S, Vepuri SB, Revanasiddappa HD, Devarajegowda HC. Bis[N,N-dimethyl-1-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propan-2-aminium] tetrakis(thiocyanato-κN)cobaltate(II). Acta Crystallogr E Struct Rep Online. 2010 Jun 16;66(7):m772–3. doi: 10.1107/s1600536810021367.
摘要:Melwanki MB, Seetharamappa J. Spectrophotometric studies on the investigation of chromium in environmental samples. Indian J Environ Health. 2003 Jan;45(1):25–8.
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