CAS: 3947-62-4; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-Hydroxytetrahydro-2H-Pyran-3,4,5-Triyl Triacetate

该化合物是一种高度功能化的碳水化合物衍生物,其特点是其乙酰保护氢氧化物组和C-6位置的免费氢氧化物组.该化合物在合成有机化学中特别宝贵,因为它是合成精密的中间体,可以进行同步反应和合成复杂的寡叶酸盐. 乙酰组在化学转化期间提供了稳定性和选择性,而免费的氢氧基允许进一步进行特定地点的修改.其立体化学结构确保精确控制构建胶水化合物连接,使其在医药化学,糖理学和材料科学应用中有用.该化合物的纯度和完善配置对于研究和工业环境中的再生结果至关重要.

结构式图片

相似化合物

22415-91-4 83-87-4 10343-06-3

上下游产品

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合成工艺路线路线简述

    Alpha-D-半乳糖置于三丁基氯化锡,氢溴酸,Sodium Cyanoborohydride,叔丁醇体系中,用 吡啶,乙醚,溶剂黄146 用作溶剂,化学反应 116.0H,反应生成2,3,4,6-四-O-乙酰-β-D-吡喃葡萄糖
    参考文献: Derivatives Of Uridine Phosphate And Their Uses In Protein Binding Assays[fr] Composés Et Leurs Utilisations Dans Des Dosages De Liaison Aux Protéines
    标题: Derivatives Of Uridine Phosphate And Their Uses In Protein Binding Assays[fr] Composés Et Leurs Utilisations Dans Des Dosages De Liaison Aux Protéines

    海关参考信息

    专利信息


    专利号:US-6723843-B2
    优先权日:1996-08-26
    标题:Oligosaccharide synthesis
    发明人:TOTH ISTVAN; DEKANY GYULA; KELLAM BARRY
    权利人:ALCHEMIA PTY LTD
    摘要:The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to couple saccharide groups of both the O-glycoside and N-glycoside type to a polymer support. The invention provides reagents, reagent kits and methods for solid-phase oligosaccharide synthesis.

    专利号:US-6319695-B1
    优先权日:1991-10-15
    标 题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
    发明人:WONG CHI-HUEY; ICHIKAWA YOSHITAKA; SHEN GWO-JENN; LIU KUN-CHIN
    权利人:SCRIPPS RES INSITUTE
    摘要:This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides are then used to produce sugar nucleotides that are in turn used as donor sugars for glycosylation of acceptor carbohydrates. Especially preferred herein is the use of a disclosed method for fucosylation.

    专利号:US-8513395-B2
    优先权日:2005-06-15
    标题:Method for the synthesis of anthocyanins
    发明人:BAKSTAD EINAR
    权利人:BAKSTAD EINAR; BIOSYNTH AS
    摘要:The present invention relates to methods of preparing anthocyanins, and methods of preparing precursors of anthocyanins. The methods utilize a coupling reaction between a sugar and a suitable electrophilic precursor to form Eastern half intermediates that are then reacted with Western half intermediates to form the target anthocyanins. Some Eastern half intermediates and electrophilic precursors also form part of the invention.

    专利号:US-4122092-A
    优先权日:1977-08-25
    标 题:Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone
    发明人:KENDE ANDREW S; RUTLEDGE PETER S
    权利人:UNIV ROCHESTER
    摘要:Efficient total syntheses of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone are described. These compounds are intermediates in the preparation of known antineoplastic agents.

    专利号:US-9023813-B2
    优先权日:2011-04-13
    标题:Synthesis and use of glycoside derivatives of propofol
    发明人:SHULL BRIAN; BALDWIN JOHN; GOPALASWAMY RAMESH; HAROON ZISHAN
    权利人:SHULL BRIAN; BALDWIN JOHN; GOPALASWAMY RAMESH; HAROON ZISHAN; NUTEK PHARMA LTD
    摘要:The present invention relates to methods and compositions for the synthesis, production, and use of pro-drug propofol analogs. This invention relates to a method for the production of a broad group of glycosylated propofol carbohydrate derivatives.

    专利号:US-10787576-B2
    优先权日:2015-04-30
    标 题 :Method for the preparation of a coating comprising oligomeric alkynes
    发明人:FRAUENRATH HOLGER; SCHRETTL STEPHEN; SCHULTE BJOERN; LETERRIER YVES
    权利人:ECOLE POLYTECHNIQUE FED DE LAUSANNE EPFL EPFL TTO
    摘要:The invention relates to a method for the preparation of a coating comprising at least one coating layer on a substrate, the method comprising the steps of a. providing monomers of the type R—(N) x -(L) m -(Câ•?C) n -(L′) o -(N′) y —R′, wherein R is a head moiety, R′ is a tail moiety, (C≡C) n is an oligoyne moiety, L and L′ are linker moieties, N and N′ independently are branched or unbranched optionally substituted C 1 -C 25 alkyl moieties optionally containing 1 to 5 heteroatoms, x, m, o, and y are independently 0 or 1, n is 4 to 12, and wherein the head moiety allows for an interaction with the surface of the substrate; b. bringing the monomers into contact with the substrate wherein the interaction of the head moieties of the monomers with the surface of the substrate induces at least a part of the monomers to align in a defined manner thereby forming a film on the surface and bringing the oligoyne moieties of the monomers into close contact with each other; c. inducing a reaction between oligoyne moieties by providing an external stimulus so as to at least partially cross-link the aligned monomers, thereby forming a coating layer on the substrate. The invention further relates to a coating obtainable according to the method of the invention, the use of a coating obtainable according to the method of the invention, a substrate comprising a coating obtainable according to the invention and the use of solid substrate. The invention further relates to a method for the synthesis ofthe monomers according to the invention.
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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
    摘要:Milata, V.; Rádl, S.; Voltrová, S., Science of Synthesis, (2008) 32, 625.
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