CAS: 380430-49-9; (4-Boc-Aminophenyl)Boronic Acid

上下游产品

CAS号330793-01-6 N-B°C-4-氨基苯硼酸频哪醇酯 | CAS号487-89-8 3-吲哚甲醛 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号89415-43-0 4-氨基苯硼酸 | CAS号848853-68-9 tert-butyl 4'-m... | CAS号1137-77-5 4-(4-甲氧基苯基)苯胺 | CAS号1246203-34-8 4-[4-[2-(difluo... | CAS号1246203-33-7 tert-butyl N-[4... | CAS号118727-34-7 1,3,5-三(4-氨苯基)苯 | CAS号1246203-35-9 N-[4-[4-[2-(dif...

N-Boc-4-氨基苯硼酸频哪醇酯置于盐酸,Polystyrene Boronic Acid体系中,用 乙腈 作为反应溶剂,化学反应 18.0H,以78%的收率获得产物4-(N-Boc-氨基)苯硼酸
参考文献:Deprotection Of Pinacolyl Boronate Esters By Transesterification With Polystyrene-boronic Acid
标题:Deprotection Of Pinacolyl Boronate Esters By Transesterification With Polystyrene-boronic Acid
摘要:Mild Deprotection Of Pinacolyl Boronate Esters To The Corresponding Boronic Acids Was Achieved In The Presence Of Excess Polystyrene-Boronic Acid Via A Transesterification Process. The Procedure Allows For The Cleavage Of Pinacolyl Boronate Esters In The Presence Of Sensitive Functional Groups. Crown Copyright (C) 2004 Published By Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tetlet.2004.07.014

专利信息

专利号:US-2022356182-A1
优先权日:2009-03-27
标题 :Inhibitors of hepatitis c virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOLL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-2025082793-A1
优先权日:2021-11-09
标 题 :Macrocyclic compounds and methods of making the same
发明人：CLEATOR EDWARD; MATON WILLIAM MARC; SALTER RHYS
权利人:JANSSEN BIOTECH INC
摘要:The present invention is directed to the preparation of key intermediates and synthesis of compounds (macrocyclic compounds) and pharmaceutically acceptable salts thereof, immunoconjugates, radioimmunoconjugates thereof, pharmaceutical compositions containing said compounds and immunoconjugates, radioimmunoconjugates thereof.

专利号:US-11053243-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOIL RICHARD; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-9090661-B2
优先权日:2009-03-27
标 题:Inhibitors of hepatitis C virus replication
发明人：COBURN CRAIG A; MCCAULEY JOHN A; LUDMERER STEVEN W; LIU KUN; VACCA JOSEPH P; WU HAO; HU BIN; SOLL RICHARD; SUN FEI; WANG XINGHAI; YAN MAN; ZHANG CHENGREN; ZHENG MINGWEI; ZHONG BIN; ZHU JIAN
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.