CAS: 221908-17-4; Sodium 2,3,5,6-Tetrafluoro-4-Hydroxybenzenesulfonate

该化合物是一种氟化芳香磺酸化合物,其特点是,由于苯环的四氟替代物具有高电子排层特性,其特点是苯环的四氟替代物具有高电子阻燃性,氢氧基和磺酸盐组的存在提高了其在极地溶剂中的溶解性,使其适合于有机合成的应用,特别是作为特殊化学品制作过程中的中间体.其强电缺性能有利于核生殖替代反应,而全氟辛烷磺酸会提高稳定性和处理能力.该化合物因其在制药和农用化学研究中的多用途性而受到重视,在这种研究中,为了增强再活性和代物稳定性,常常需要氟介质.

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合成工艺路线路线简述

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    专利信息


    专利号:US-2018105546-A1
    优先权日:2011-06-14
    标题:Methods for Chemical Synthesis of Biologically Active Compounds Using Supramolecular Protective Groups and Novel Compounds Obtainable Thereby

    专利号:US-2014243280-A1
    优先权日:2011-06-14
    标题:Methods for chemical synthesis of biologically active compounds using supramolecular protective groups and novel compounds obtainable Thereby

    专利号:US-9676787-B2
    优先权日:2012-08-28
    标 题 :Benzopyrylium compounds
    发明人:HERMANSON GREG; CZERNEY PETER T; DESAI SURBHI; WENZEL MATTHIAS S; LEHMANN FRANK G; NLEND MARIE CHRISTINE
    权利人:HERMANSON GREG; CZERNEY PETER T; DESAI SURBHI; WENZEL MATTHIAS S; LEHMANN FRANK G; NLEND MARIE CHRISTINE; PIERCE BIOTECHNOLOGY INC; DYOMICS GMBH
    摘要:Compounds used as labels with properties comparable to known fluorescent compounds. The compounds are conjugated to proteins and nucleic acids for biological imaging and analysis. Synthesis of the compounds, formation and use of the conjugated compounds, and specific non-limiting examples of each are provided.

    专利号:EP-2721046-A1
    优先权日:2011-06-14
    标题:Methods for chemical synthesis of biologically active compounds using supramolecular protective groups and novel compounds obtainable thereby

    专利号:WO-2012173477-A1
    优先权日:2011-06-14
    标题 :Methods for chemical synthesis of biologically active compounds using supramolecular protective groups and novel compounds obtainable thereby

    专利号:EP-2721046-B1
    优先权日:2011-06-14
    标题 :Methods for chemical synthesis of biologically active compounds using supramolecular protective groups and novel compounds obtainable thereby
    发明人:HERRMANN ANDREAS; BASTIAN ANDREAS ALEXANDER; MARCOZZI ALESSIO
    权利人:UNIV GRONINGEN

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