CAS: 20379-59-3; 1-Azido-1-Deoxy-β-D-Glucopyranoside

上下游产品

D-Glucose 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl azide 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl chloride D-glucose 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-glucopyranosyl azide 2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl azide N-(β-D-glucopyranosyl)triphenylphosphine imide (2R,3R,4S,5S,6R)-2-Azido-6-trityloxymethyl-tetrahydro-pyran-3,4,5-triol

专利信息

专利号:US-2023212216-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins
发明人：MORRIS ALEXANDER REDFERN; SUTOV GRIGORIJ; BRUNE KARL DIETRICH
权利人:GENIE BIOTECH UK LTD
摘要:Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.

专利号:US-12291547-B2
优先权日:2019-06-14
标题 :Synthesis of 3-azido-3-deoxy-D-galactopyranose
发明人：GIGUÈRE DENIS; ST-GELAIS JACOB; DENAVIT VINCENT
权利人:UNIV LAVAL
摘要:The present application provides a synthetic method for production of 3-azido-3-deoxy-D-galactopyranose. Also provided are methods of using the 3-azido-3-deoxy-D-galactopyranose in the manufacture of galactoside galectin antagonists, such as TD139 (GB0139), GB1107, GB2064, and GB1211.

专利号:US-2022251129-A1
优先权日:2019-06-14
标题:Synthesis of 3-azido-3-deoxy-d-galactopyranose

专利号:WO-2020248068-A1
优先权日:2019-06-14
标 题 :Synthesis of 3-azido-3-deoxy-d-galactopyranose

专利号:AU-2020409711-A1
优先权日:2019-12-20
标题 :Synthesis of lactone derivatives and their use in the modification of proteins

专利号:EP-4076533-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins