CAS: 110642-44-9; 3-(((2S,3R,4R,5R,6S)-4,5-Dihydroxy-6-Methyl-3-(((2S,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyltetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2-yl)Oxy)-5-Hydroxy-2-(4-Methoxyphenyl)-8-(3-Methylbut-2-En-1-yl)-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxyme

该化合物是主要来自中国传统药用草药Epimed(俗称"山羊weed")的裂变类化合物,因其潜在的药理特性而得到承认,包括抗氧化剂,抗炎和...

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    1: Li J, Chen W, Wang Y, Yin H. An LC-MS/MS method for simultaneous quantification of 11 components of Xian-Xiong-Gu-Kang in the plasma of osteoarthritic rats and pharmacokinetic analysis. J Sep Sci. 2021 Jun 29. doi: 10.1002/jssc.202100132. Epub ahead of print.
    202:114140. doi: 10.1016/j.jpba.2021.114140. Epub 2021 May 13. 56(5):e4711. doi: 10.1002/jms.4711. 16(1):26. doi: 10.1186/s13020-021-00435-0.
    5: Huang M, Wei Y, Dong J. Epimedin C modulates the balance between Th9 cells and Treg cells through negative regulation of noncanonical NF-κB pathway and MAPKs activation to inhibit airway inflammation in the ovalbumin-induced murine asthma model. Pulm Pharmacol Ther. 2020 Dec;65:102005. doi: 10.1016/j.pupt.2021.102005. Epub 2021 Feb 23. 165(Pt A):1361-1372. doi: 10.1016/j.ijbiomac.2020.10.018. Epub 2020 Oct 10. 45(11):2502-2508. Chinese. doi: 10.19540/j.cnki.cjcmm.20200329.113. 10(6):932. doi: 10.3390/biom10060932.

    合成参考文献


    参考文献:10.1016/0031-9422(96)00187-2
    摘要:Li WK, Zhang RY, Xiao PG. Flavonoids from Epimedium wanshanense. Phytochemistry. 1996 Sep;43(2):527–30. doi: 10.1016/0031-9422(96)00187-2.
    参考文献:10.1002/bmc.3174
    摘要:Cui L, Sun E, Zhang Z, Tan X, Xu F, Jia X. Metabolite profiles of epimedin C in rat plasma and bile by ultra-performance liquid chromatography coupled with quadrupole-TOF-MS. Biomed Chromatogr. 2014 Oct;28(10):1306–12. doi: 10.1002/bmc.3174.
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