CAS: 1073-05-8; 1,3,2-Dioxathiane2,2-Dioxide

相似化合物

1755-97-1 1072-53-3 4176-55-0

上下游产品

CAS号504-63-2 1,3-丙二醇 | CAS号4176-55-0 亚硫酸丙烯酯 | CAS号109-64-8 1,3-二溴丙烷 | CAS号628-66-0 1,3-丙二醇二乙酸酯 | CAS号77-78-1 硫酸二甲酯 | CAS号107-18-6 烯丙醇 | CAS号30684-07-2 Benzenepropanam... | CAS号92764-21-1 N,N-二甲基-N-[3-(硫...

1,3-丙二醇置于ruthenium Trichloride Sodium Periodate,氯化亚砜体系中,化学反应生成1,3-丙二醇环硫酸酯
参考文献:A New Route For The Synthesis Of Amphiphilic And Water-Soluble Ligands: Mono-And Di-Tertiary Phosphines Having An Alkylene Sulfate Chain
标题:A New Route For The Synthesis Of Amphiphilic And Water-Soluble Ligands: Mono-And Di-Tertiary Phosphines Having An Alkylene Sulfate Chain
摘要:环状硫酸酯与lipph2反应生成一系列新的两亲性或水溶性配体:具有一个或两个亚烷基硫酸酯链的单三级膦以及具有一个或两个亲水性尾部与桥头碳原子相连的双三级膦;阴离子性铑i配合物(硫酸酯膦)2Rh(cod)和(硫酸酯双膦)rh(cod)在液-液两相催化中应用于苯乙烯和1-辛烯的氢甲酰化反应.
Doi:10.1039/a706602C

专利信息

专利号:US-6277982-B1
优先权日:1999-08-20
标题:Alkylation of alcohols, amines, thiols and their derivatives by cyclic sulfate intermediates
发明人：FRASER ALLISTER S; MANOHARAN MUTHIAH; COOK PHILLIP DAN; JUNG MICHAEL E; KAWASAKI ANDREW M
权利人:ISIS PHARMACEUTICALS INC
摘要:Methods for the alkylation of alcohols, amines and thiols by the use of cyclic sulfates are disclosed. The alkylated sulfates formed are versatile intermediates which may be further elaborated by methods of the invention. In particular, methods for the alkylation of the 2′, 3′ or 5′-hydroxy position of nucleosides and nucleoside analogs with cyclic sulfates to form the 2′, 3′ or 5′-O-alkyl sulfate modified compounds are disclosed. Displacement of the 2′,3′ or 5′-O-sulfate with a nucleophile provides 2′, 3′ or 5′-O-modified nucleosides and nucleoside analogs useful for the synthesis of oligomeric compounds having improved hybridization affinity and nuclease resistance.

专利号:US-11780834-B2
优先权日:2018-06-21
标题:Solid forms of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3- yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol and processes for preparing fused tricyclic compounds comprising a substituted phenyl or pyridinyl moiety, including methods of their use
发明人：CHUNG CHEOL KEUN; XU JIE; IDING HANS; CLAGG KYLE; DALZIEL MICHAEL; FETTES ALEC; GOSSELIN FRANCIS; LIM NGIAP-KIE; MCCLORY ANDREW; ZHANG HAIMING; CHAKRAVARTY PAROMA; NAGAPUDI KARTHIK; ROBINSON SARAH
权利人:HOFFMANN LA ROCHE; GENENTECH INC
摘要:Provided herein are solid forms, salts, and formulations of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, processes and synthesis thereof, and methods of their use in the treatment of cancer.