CAS: 693-05-0; 3-(Methylamino)Propanenitrile

相似化合物

706-03-6 53588-95-7 2679-14-3

上下游产品

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3-甲基-2-恶唑烷酮置于potassium Cyanide,18-冠醚-6体系中,化学反应 8.0H,以50%的收率获得产物3-甲胺基丙腈
参考文献:由2-恶唑烷酮与氰化物离子开环合成3-氨基丙腈的新方法
标题:由2-恶唑烷酮与氰化物离子开环合成3-氨基丙腈的新方法
摘要:在18-冠-6存在下,氰离子对2-恶唑烷酮的5-位的亲核攻击产生了3-氨基丙腈.
DOI:10.1016/j.Tetlet.2009.06.014

专利信息

专利号:US-8557979-B2
优先权日:2004-06-10
标题 :Carbapenem antibacterials with gram-negative activity and processes for their preparation
发明人：CHOI WOO-BAEG; KOWALIK EWA
权利人:CHOI WOO-BAEG; KOWALIK EWA; FOB SYNTHESIS INC
摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.

专利号:WO-2009001369-A1
优先权日:2007-06-22
标 题 :An improved process for the preparation of alfuzosin hydrochloride
发明人：DEO KESHAV; DESAI SANJAY; RATHOD DHIRAJ MOHANSINH; PARIKH CHIRAG CHANDRAKANT; PATEL RIPALKUMAR KANTIBHAI
权利人:ALEMBIC LTD; DEO KESHAV; DESAI SANJAY; RATHOD DHIRAJ MOHANSINH; PARIKH CHIRAG CHANDRAKANT; PATEL RIPALKUMAR KANTIBHAI
摘要:The present invention relates to an improved process for the preparation of Alfuzosin hydrochloride of formula (I) comprising a step of reacting compound of formula (IV) with compound of formula (V) in presence of aprotic solvent to obtain compound of formula (III) which is a useful intermediate for synthesis of Alfuzosin hydrochloride of formula (I).

专利号:US-7220884-B2
优先权日:2004-02-10
标 题 :Hydroaminomethylation of olefins
发明人：BRIGGS JOHN R; WHITEKER GREGORY T; KLOSIN JERZY
权利人:DOW GLOBAL TECHNOLOGIES INC
摘要:The present invention relates to a method comprising the step of contacting under hydroaminomethylation conditions, an olefin, an amine, a rhodium-phosphorous ligand, and synthesis gas (syngas). In particular, it has been discovered that, under some circumstances, a neutral rhodium-monodentate phosphite ligand is prescribed. The invention provides a simple way of making, in high yields and regiospecificity, a variety of products, including pharmacologically active products such as ibutilide, terfenadine, and fexofenadine, and derivatives thereof.

专利号:US-2008039473-A1
优先权日:2006-08-08
标题:Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:The present disclosure is directed to modulators of alpha-adrenergic receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the use of such compounds for the treatment and/or management of hypertension, cardiac failure, prostatitis, and benign prostatic hyperplasia, and any other condition in which it is beneficial to modulate an alpha-adrenergic receptor.

专利号:CN-115414942-A
优先权日:2022-09-23
标题 :Catalyst for synthesis of N,N-bis(3-aminopropyl)methylamine, preparation method and application thereof

专利号:RU-2105007-C1
优先权日:1991-10-10
标题:Method of synthesis of benzo-[b]-naphthyridine derivatives and derivatives of benzo-[b]-naphthyridines