CAS: 563-45-1; 3-Methylbut-1-Ene

上下游产品

diethyl sulfate isopentyl ether 2-methyl-but-2-ene 1,2-dibromo-3-methylbutane isoprene 1,1,1,3-tetrachloro-4-methylpentane isoamyl thioacetate phenyl (2-methyl)but-2-yl sulphide

2-甲基-1-丁烯-3-炔置于一氧化碳,1% Pd/γ-Al2O3,氢气体系中,74.84 °C,100.0 Kpa 条件下,反应生成 3-甲基-1-丁烯
参考文献:共轭烯-炔和二烯化合物的非均相催化加氢中的选择性模式
标题:共轭烯-炔和二烯化合物的非均相催化加氢中的选择性模式
摘要:共轭烃(烯-炔和二烯化合物)的非均相催化加氢中的选择性控制是一项艰巨的任务.有关该主题的可用研究主要围绕1,3-丁二烯作为底物,钯作为催化剂,而更多精细的运动场分子和其他金属仍未开发.这项研究研究了pd,Pb中毒的pd,Co改性的pd,Cu上戊烯(2-甲基-1-丁烯-3-炔)和异戊二烯(2-甲基-1,3-丁二烯)的气相加氢,Ni和双金属cu Ni催化剂.化学选择性,区域选择性,完全氢化和c在不同的入口氢碳氢比和转化度下,催化体系的c键形成/断裂足迹已得到合理化.为了分析(i)异构化对在戊烯/异戊二烯加氢中观测到的单烯烃分布的影响和(II)部分共轭的问题,进行了3-甲基丁炔和1-戊烯-4-炔氢化的补充研究.烯炔加氢.我们的结果导致人们对多不饱和烃的氢化有了更深入的了解,并为这一实际重要的反应类别设计了更具选择性的非均相催化剂和相关工艺.
DOI:10.1016/j.Jcat.2011.10.003

专利信息

专利号:US-8273790-B2
优先权日:2005-01-14
标 题:Exo-selective synthesis of himbacine analogs
发明人：THIRUVENGADAM TIRUVETTIPURAM K; SUDHAKAR ANANTHA; LIM NGIAP KIE; KWOK DAW-IONG; WU GEORGE G; WANG TAO; HUANG MINGSHENG; GREEN MICHAEL D
权利人:THIRUVENGADAM TIRUVETTIPURAM K; SUDHAKAR ANANTHA; LIM NGIAP KIE; KWOK DAW-IONG; WU GEORGE G; WANG TAO; HUANG MINGSHENG; GREEN MICHAEL D; SCHERING CORP
摘要:This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. The compounds produced thereby are useful as thrombin receptor antagonists. The chemistry disclosed herein is exemplified in the following synthesis sequence:

专利号:US-7973171-B2
优先权日:2005-06-13
标题:Process for synthesis of dialkoxyorganoboranes
发明人：BURKHARDT ELIZABETH; ATKINS WILLIAM
权利人:BURKHARDT ELIZABETH; ATKINS WILLIAM
摘要:The invention relates to a process for the synthesis of dialkoxyorganoboranes, in particular to a process for the synthesis of dialkoxyorganoboranes by an ester exchange reaction. Moreover, the invention relates to a process for the synthesis of organo-oxazaborolidine catalysts (organo-CBS) and of trialkylboroxins. Furthermore, the invention relates to methods of using dialkoxyorganoboranes for the preparation of organo-CBS catalysts and in Suzuki-type coupling reactions.

专利号:US-2024228455-A1
优先权日:2021-04-27
标 题 :Synthesis of cbn and cbnv
发明人：KAVARANA MALCOLM J
权利人:TEEWINOT LIFE SCIENCES CORP
摘要:The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.

专利号:US-9126995-B2
优先权日:2011-11-08
标题:Method for catalytic asymmetric synthesis of optically active isoxazoline compound and optically active isoxazoline compound
发明人：TOYAMA KEN-ICHI; MORIYAMA YUJI; MATOBA KAZUTAKA; YAOSAKA MANABU; IKEDA EITATSU
权利人:NISSAN CHEMICAL IND LTD
摘要:There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,β-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

专利号:US-11512303-B2
优先权日:2017-05-27
标 题 :Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids
发明人：CHEN HAIBIN; BONG YONG KOY; XU QING; ZHOU AMENG; SHEN TIANRAN; YANG JIADONG; YANG ZHUHONG
权利人:ENZYMASTER NINGBO BIO ENG CO LTD
摘要:The present invention provides engineered polypeptides that are useful for the asymmetric synthesis of β-hydroxy-α-amino acids under industrial-relevant conditions. The engineered polypeptides disclosed in this invention were developed through directed evolution based on the ability of catalytic synthesis of (2S, 3R)-2-amino-3-hydroxy-3-(4-nitrophenyl) propanoic acid. The present disclosure also provides polynucleotides encoding engineered polypeptides, host cells capable of expressing engineered polypeptides, and methods of producing β-hydroxy-α-amino acids using engineered polypeptides. Compared to other processes of preparation, the use of the engineered polypeptides of the present invention for the preparation of β-hydroxy-α-amino acids results in high purity of the desired stereoisomers, mild reaction conditions, low pollution and low energy consumption. So, it has good industrial application prospects.

专利号:US-11046978-B2
优先权日:2016-03-16
标 题:Synthesis of isoprenoids and derivatives
发明人：GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
权利人:UNIV RICE WILLIAM M
摘要:This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyioin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5-phosphate (DXP) pathways for generating isoprenoid precursors such as isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), and geranyl pyrophosphate (GPP). These pathways have the potential for better carbon and or energy efficiency than native pathways. Both decarboxylative and non-carboxylative condensations are utilized, enabling product synthesis from a number of different starting compounds. These condensation reactions serve as a platform for the synthesis of isoprenoid precursors when utilized in combination with a variety of metabolic pathways and enzymes for carbon rearrangement and the addition/removal of functional groups. Isoprenoid alcohols are key intermediary products for the production of isoprenoid precursors in these novel synthetic metabolic pathways.