CAS: 55552-70-0; 3-Furanboronic Acid

上下游产品

3-bromofurane Triisopropyl borate tetrahydroxydiboron Methyl 5-(3-Furyl)nicotinate benzamideN-2-(3-furyl)benzylbenzamide 7-Chloro4-(furan-3-yl)quinoline 2-(3-furyl)indole-3-carbaldehyde

3-溴呋喃置于四羟基二硼,1,3-Bis[(Diphenylphosphino)Propane]Dichloronickel(II),N,N-二异丙基乙胺,三苯基膦体系中,用 乙醇 作为反应溶剂,化学反应 4.0H,反应生成 3-呋喃硼酸
参考文献:镍催化四羟基二硼 [b2(Oh)4] 卤化物和拟卤化物的硼化反应
标题:镍催化四羟基二硼 [b2(Oh)4] 卤化物和拟卤化物的硼化反应
摘要:芳基硼酸作为试剂和目标结构在各种有用的应用中变得越来越重要.最近,报道了使用原子经济的四羟基二硼(bba)试剂在钯催化下合成芳基硼酸.钯的高成本,加上钯和铜催化工艺的一些限制,促使我们开发一种替代方法.因此,已经制定了使用四羟基二硼(bba)对芳基和杂芳基卤化物和拟卤化物进行镍催化的硼基化反应.该反应被证明具有广泛的官能团耐受性并适用于许多杂环体系.据我们所知,这里提供的例子代表了在室温下进行的唯一有效的镍催化宫浦硼化反应.
DOI:10.1021/jo401104Y

专利信息

专利号:WO-2023207921-A1
优先权日:2022-04-25
标题 :Taxamairin analogs and methods of preparation and use thereof
发明人：LEE CHI SING; GE SIYUAN; ZHUANG ANDREW-GO
权利人:UNIV HONG KONG BAPTIST UNIV
摘要:Taxamairin analogs useful in the treatment of cancer, pharmaceutical compositions including the same, methods of use thereof, and methods of preparation are provided. An efficient and scalable semi-synthesis of taxamairin compounds and analogs thereof from readily available commercial starting materials is provided. The synthesis involves low cost and relatively non-toxic reagents and is capable of synthesizing taxamairin A and taxamairin B and analogs thereof on multi-gram scale in yields up 12%and 21%, respectively.

专利号:US-11512075-B2
优先权日:2017-06-14
标 题:Synthesis of 20-nor-salvinorin A
发明人：SHENVI RYAN; ROACH JEREMY; SASANO YUSUKE; BOHN LAURA; SCHMID CULLEN
权利人:SCRIPPS RESEARCH INST
摘要:The invention provides 20-nor-salvinorin A, an analog of the kappa-opioid agonist salvinorin A. The 20-nor-salvinorin A is an active kappa-opioid modulator and can be used for treatment of medical conditions wherein modulation of the kappa-opioid receptor is medically indicated, such as pain, pruritis, depression, or inflammation, or conditions implicating perception and consciousness. 20-nor-salvinorin A can be less additive when used in treatment compared to a mu-opioid receptor agonist, and 20-nor-salvinorin A is more stable in vivo than is parent compound salvinorin A. The invention further provides synthetic intermediates and procedures for preparation of 20-nor-salvinorin A.

专利号:US-11767302-B2
优先权日:2020-10-01
标题 :Reagents and methods for tetrazine synthesis
发明人：FOX JOSEPH M; LAMBERT WILLIAM; FANG YINZHI; AM ENDE CHRISTOPHER WILLIAM; MAHAPATRA SUBHAM; XIE YIXIN; WANG CHUANQI
权利人:UNIV DELAWARE
摘要:Disclosed herein are mono- and di-substituted tetrazines and methods of their preparation and converting an oxetanyl ester to a thio-substituted tetrazine, which is then converted to a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine.

专利号:US-8338451-B2
优先权日:2008-03-21
标 题 :Polysubstituted derivatives of 2-heteroaryl-6-phenylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof
发明人：DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO
权利人:DE PERETTI DANIELLE; EVANNO YANNICK; LARDENOIS PATRICK; MACHNIK DAVID; RAKOTOARISOA NATHALIE; ALMARIO GARCIA ANTONIO; SANOFI SA
摘要:Compounds of formula (I): n nwherein R, R 1 , R 2 , R 3 , R 4 and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

专利号:US-8221719-B2
优先权日:2007-09-05
标 题:Luminescent lanthanide (III) chelates, chelating agents and conjugates derived thereof
发明人：PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI
权利人:PEURALAHTI JARI; HOVINEN JARI; KETOLA JANNE; JAAKKOLA LASSI; MUKKALA VELI-MATTI; LIITTI PAEIVI; WALLAC OY
摘要:This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.

专利号:US-2020131162-A1
优先权日:2017-06-14
标题:Synthesis of 20-nor-salvinorin a