CAS: 481-06-1; α-Santonin

上下游产品

CAS号6308-44-7 EUDESMATRIENOLI... | CAS号14794-69-5 (3,6,9-trimethy... | CAS号571-58-4 1,4-二甲基萘 | CAS号1618-82-2 Naphtho[1,2-b]f... | CAS号1567-89-1 丙酮-2,4-二硝基苯腙 | CAS号1527-96-4 巴豆醛2,4-二硝基苯腙 | CAS号59444-48-3 1,4a,7a-trimeth...

1,2-二氢-Alpha-山道年置于吡啶,Chromium(Vi) Oxide,Sodium Tetrahydroborate,Cerium(Iii) Chloride,五羰基铁,三甲基脲,硫酸,Potassium Carbonate,间氯过氧苯甲酸,2,3-二氯-5,6-二氰基-1,4-苯醌体系中,用 苯 作为反应溶剂,化学反应生成 山道年
参考文献:A Formal Synthesis Of L-.Alpha.-Santonin From Chiral .Alpha.,.Beta.-Epoxyeudesmanolide Via Enzyme-Cayalyzed Hydrolysis.
标题:A Formal Synthesis Of L-.Alpha.-Santonin From Chiral .Alpha.,.Beta.-Epoxyeudesmanolide Via Enzyme-Cayalyzed Hydrolysis.
摘要:通过酵母处理(+/-)-3__-,分别得到了(4S,5R)-环氧-(3S)-羟基-(10S)-7α,11βh-桉烷-6α,12-内酯4__-和(4R,5S)-环氧-(3S)-羟基-(10R)-7β,11αh-桉烷-6β,12-内酯5__-;通过脂肪酶处理(+/-)-8__-,制备了(3S)-乙酰氧基-(4S,5R)-环氧-(10S)-7α,11βh-桉烷-6α,12-内酯8__-.通过使用手性关键中间体(10S)-8__-(通过不对称水解(+/-)-8__-制备)的短步骤合成,成功完成了l-α-山道年(9)及其δ4(14)异构体(10和11)的新全合成.
DOI:10.1248/cpb.42.1160

专利信息

专利号:US-2011296543-A1
优先权日:2006-06-01
标题:Nucleic acids and proteins and methods for making and using them
发明人：CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON
权利人:CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON; UNIV CALIFORNIA; CALIFORNIA INST OF TECHN; VERENIUM CORP
摘要:The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.