CAS: 4318-56-3; 6-Chloro-3-Methylpyrimidine-2,4(1H,3H)-Dione

相似化合物

6972-27-6 31737-09-4 887581-47-7

上下游产品

CAS号2565-47-1 1-甲基巴比妥酸 | CAS号882872-13-1 6-hydroxy-3-met... | CAS号141-82-2 丙二酸 | CAS号598-50-5 甲基脲 | CAS号112069-52-0 6-(3-chloroanil... | CAS号112069-51-9 6-(2-chloroanil... | CAS号5759-63-7 3-甲基-6-甲基氨基尿嘧啶 | CAS号144294-61-1 3-Methyl-6-(1-e... | CAS号207128-61-8 N-[5-(butylcarb... | CAS号2850-37-5 1H-Purine-2,6-d... | CAS号865758-96-9 2-[(6-氯-34-二氢-3... | CAS号6972-27-6 6-氯-1,3-二甲基尿嘧啶 | CAS号32502-63-9 3-Phenyltoxoflavin | CAS号42285-61-0 3-(4-chlorophen...

6-Hydroxy-1-Methylpyrimidine-2,4-Dione置于三氯氧磷体系中,用 乙腈 作为反应溶剂,化学反应 0.33H,以80%的收率获得产物6-氯-3-甲基尿嘧啶
参考文献:微波辅助合成3-芳基-嘧啶基[5,4-E] [1,2,4]三嗪-5,7(1 H,6 H)-二酮文库:毒黄素的衍生物
标题:微波辅助合成3-芳基-嘧啶基[5,4-E] [1,2,4]三嗪-5,7(1 H,6 H)-二酮文库:毒黄素的衍生物
摘要:描述了一种平行合成的毒素类黄素衍生物的文库.微波辅助方法涉及从头产生杂环支架,并允许容易地引入各种片段.
DOI:10.1016/j.Tetlet.2010.09.044

专利信息

专利号:WO-2015092739-A1
优先权日:2013-12-19
标题:Process for preparation of alogliptin
发明人：VADALI LAKSHMANA RAO; DASARI SRINIVASA RAO; MANUKONDA SESHADRI RAO; PONDURI RAJASEKHAR
权利人:MYLAN LAB LTD
摘要:Processes for the preparation of alogliptin benzoate are disclosed. The present disclosure also provides intermediates useful in the synthesis of alogliptin benzoate.

专利号:CN-112341432-A
优先权日:2020-11-13
标题 :A kind of synthesis technique of alogliptin benzoate

专利号:CN-112939937-B
优先权日:2021-03-01
标 题:Synthesis process of trelagliptin succinate

专利号:CN-112552281-A
优先权日:2020-12-07
标 题:A kind of synthesis technology of raw material medicine of troglitatin succinate

专利号:CN-105541793-A
优先权日:2016-01-04
标题:Synthetic method of trexagliptin, trexagliptin synthesized by the method and trexagliptin synthesis intermediate

专利号:US-12233062-B2
优先权日:2018-09-26
标 题 :Heterocyclic derivatives useful as SHP2 inhibitors
发明人：HAN HUIFENG; GAO PANLIANG; MA CUNBO; KANG DI
权利人:JACOBIO PHARMACEUTICALS CO LTD
摘要:This invention provides a compound of formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention provides a pharmaceutical composition comprising the said compound.