CAS: 360-03-2; A,A-Difluorobenzeneacetic Acid

上下游产品

CAS号103-80-0 苯乙酰氯 | CAS号124-38-9 二氧化碳 | CAS号98-08-8 三氟甲苯 | CAS号2248-46-6 2,2-二氟-2-苯基乙酸乙酯 | CAS号591-50-4 碘苯 | CAS号1603-79-8 苯甲酰甲酸乙酯 | CAS号101-97-3 苯乙酸乙酯 | CAS号101-41-7 苯乙酸甲酯 | CAS号2248-46-6 2,2-二氟-2-苯基乙酸乙酯

2,2-二氯-2-苯基乙腈置于sodium Hydroxide,硫酸,三氟化锑体系中,化学反应生成 α,α-二氟苯乙酸
参考文献:Jagupol'Skii; Belinskaja,Zhurnal Obshchei Khimii,1958,Vol. 28,P. 772,774; Engl. Ausg. S. 750,752
标题:Jagupol'Skii; Belinskaja,Zhurnal Obshchei Khimii,1958,Vol. 28,P. 772,774; Engl. Ausg. S. 750,752

专利信息

专利号:US-4273947-A
优先权日:1979-01-31
标 题:Hydrogenation of fluorine-containing carboxylic acids
发明人：NOVOTNY MIROSLAV
权利人:ALLIED CHEM
摘要:A process is described for the heterogeneous hydrogenation of fluorine-containing alkyl, cycloalkyl, and benzene carboxylic acids to the corresponding primary alcohols. The hydrogenation can be carried out in the liquid or vapor phase in the presence of a solid rhodium or iridium catalyst, employed as the metal, metallic oxide, or mixture thereof. In the liquid phase, the hydrogenation can be carried out batchwise under mild conditions of temperature and pressure, preferably at about 50°-150° C. and about 5-15 atmospheres, in an atmosphere containing hydrogen gas. A preferred embodiment is the hydrogenation of trifluoroacetic acid in the liquid phase to 2,2,2-trifluoroethanol, said alcohol being useful as an intermediate in the synthesis of the anesthetic, isoflurane, CF 3 CHClOCHF 2 .

专利号:EA-002100-B1
优先权日:1996-12-23
标题:CYCLOALCYL COMPOUNDS, LACTAMS, LACTONES AND RELATED COMPOUNDS CONTAINING THEIR PHARMACEUTICAL COMPOSITIONS AND METHODS OF INHIBITING THE SURVIVAL AND / OR SYNTHESIS OF β-AMYLOUS PEPTIDE SOFTWARE AGREED SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE AND SOFTWORK

专利号:US-2002045747-A1
优先权日:1996-12-23
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2002052359-A1
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting B-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2002173504-A1
优先权日:1996-12-23
标题 :Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting B-amyloid peptide release and/or its synthesis by use of such compounds

专利号:US-2004043977-A1
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds