CAS: 29457-72-5; Lithium,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluorooctane-1-Sulfonate

上下游产品

CAS号307-35-7 全氟辛基磺酰氟 | CAS号2004-14-0 三甲基硅醇锂

专利信息

专利号:US-12065460-B2
优先权日:2021-12-30
标 题 :Compositions and methods for liquid phase oligonucleotide synthesis
发明人：YANG GAOMAI; YAO YUN-CHIAO; YU DAVID; LAU ALDRICH N K
权利人:HONGENE BIOTECH CORP
摘要:Embodiments of the present application relate to polymers used as polymeric polyvalent hub for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polyvalent hub are also provided.

专利号:US-12180140-B2
优先权日:2022-12-23
标 题 :Compounds and methods for liquid phase oligonucleotide synthesis
发明人：YANG GAOMAI; XIE MIN; YANG HONGRONG; WANG SHENGDONG; LAU ALDRICH N K; ZOU RUIMING; YU DAVID
权利人:HONGENE BIOTECH CORP
摘要:The present disclosure relates to methods and compounds for liquid phase oligonucleotide synthesis employing the use of small molecules with lipophilic groups. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the compounds described herein are also provided.

专利号:US-11725073-B2
优先权日:2020-12-29
标 题:Compositions and methods for liquid phase oligonucleotide synthesis
发明人：LAU ALDRICH N K; GUAN XIAOYANG; YU DAVID
权利人:HONGENE BIOTECH CORP
摘要:Embodiments of the present application relate to polymers for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis, comprising dissolving a polyvalent hub having a plurality of functional groups in a solvent and contacting the polyvalent hub with one or more nucleoside analogs to form a first bioconjugate are also provided.

专利号:US-12134630-B2
优先权日:2022-06-21
标 题 :Compositions and methods for liquid phase oligonucleotide synthesis
发明人：YANG GAOMAI; SONG JINGSHE; WANG SHENGDONG; YAO YUN-CHIAO; YANG HONGRONG; YU DAVID; LAU ALDRICH N K
权利人:HONGENE BIOTECH CORP
摘要:Embodiments of the present application relate to polymers used as polymeric polyvalent hubs for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polymers are also provided.

专利号:WO-2024201045-A1
优先权日:2023-03-28
标题 :Apparatus and method for preparing a defined monomer sequence polymer
发明人：LIVINGSTON ANDREW; YEO JET; PARGA CATALINA
权利人:EXACTMER LTD
摘要:An apparatus for preparing a defined monomer sequence polymer, comprising a reactor vessel for synthesis of the defined monomer sequence polymer in liquid phase therein, the reactor vessel having one or more first inlets each for receiving one or more solvents and/or one or more reagents. The apparatus further comprising a first membrane assembly in fluid communication with an outlet of the reactor vessel, the first membrane assembly being configured to separate synthesised defined monomer sequence polymer from by-products of the synthesis and/or excess solvents and/or or excess reagents, wherein a first outlet of the first membrane assembly is in fluid communication with a second inlet of the reactor vessel so that separated defined monomer sequence polymer may be circulated back to the reactor vessel through the second inlet. The apparatus further comprising a thermal jacket enclosing at least part of, and arranged to heat or cool the contents of, the first membrane assembly.

专利号:US-2002055124-A1
优先权日:1998-09-23
标题:Soluble support for organic synthesis
发明人：JANDA KIM D; GRAVERT DENNIS J
权利人:SCRIPPS RESEARCH INST
摘要:Polymer supports for liquid-phase organic synthesis (LPOS) are employed in a process for transferring a chemical intermediate between immiscilbe solvents. These compounds are produced with an expanded range of solubility range in a variety of solvent systems. A sequence of normal and “livingâ€? free radical polymerizations are employed to generate a library of block copolymers possessing either block or graft architecture with initiators 100, 200 and 3 - 4 and a diverse set of vinyl monomers 5 - 9 . Novel bifunctional initiators are employed that have functional groups that independently produce free radical polymerizations to produce the block copolymers. Preferred functional groups include diazene (—Nâ•?N—) and 2,2,6,6-tetramethylpiperidinyl-1-oxy (TEMPO) moieties tethered by ester or ether linkages.