CAS: 2493-02-9; 1-Bromo-4-Isocyanatobenzene

上下游产品

CAS号32315-10-9 三光气 | CAS号106-40-1 对溴苯胺 | CAS号1836-27-7 4-溴-N-羟基苯甲酰胺 | CAS号124-38-9 二氧化碳 | CAS号14987-96-3 (4-Bromophenyli... | CAS号503-38-8 氯甲酸三氯甲酯 | CAS号586-76-5 对溴苯甲酸 | CAS号82892-00-0 N-(4-bromobenzo... | CAS号698-67-9 4-溴苯甲酰胺 | CAS号40101-31-3 N-(4-溴苯基)邻苯二甲酰亚胺 | CAS号19102-37-5 1-amino-3-(4-br... | CAS号1202047-28-6 3-(4-bromopheny... | CAS号103-71-9 异氰酸苯酯 | CAS号29209-03-8 N-(4-Bromopheny... | CAS号2400-96-6 3-(4-bromopheny... | CAS号131818-17-2 N-丁氧羰基-4-溴丙氨酸 | CAS号3408-97-7 溴杂糖醛 | CAS号153896-47-0 3H-1,2,4-TRIAZO... | CAS号214117-50-7 4-(4-溴苯基)-1H-1,...

📜N-(4-溴苯基)氨基甲酸乙酯置于phosphorus Pentoxide体系中,化学反应生成4-溴异氰酸苯酯
参考文献:Dennstedt,Chemische Berichte,1880,Vol. 13,P. 229
标题:Dennstedt,Chemische Berichte,1880,Vol. 13,P. 229

专利信息

专利号:US-4749806-A
优先权日:1984-12-28
标题:Process for the synthesis of isocyanates and of isocyanate derivatives
发明人：TKATCHENKO IGOR; JAOUHARI RABIH; BONNET MICHEL; DAWKINS GORDON; LECOLIER SERGE
权利人:POUDRES & EXPLOSIFS STE NALE
摘要:The present invention relates to a process for the synthesis of isocyanates and of isocyanate derivatives. Isocyanates are obtained by reacting an organic halide with a metal cyanate in an organic medium in the presence of a catalyst consisting of a complex of nickel with at least one organic ligand, in which complex the nickel is in the zero oxidation state. A carbamate or a urea, respectively, are obtained by a subsequent reaction with a hydroxy compound or a primary or secondary amine. Isocyanates and their derivatives are used especially either as refined synthesis agents for the production of pesticides and medications, or as monomers or comonomers for the preparation of many macromolecular compounds.

专利号:US-5569786-A
优先权日:1987-01-06
标 题 :Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated 'combretastatins'
发明人：PETTIT GEORGE R; SINGH SHEO B
权利人:UNIV ARIZONA
摘要:New antineoplastic substances have been isolated, structurally elucidated and synthesized having a general structural formula of: (I) or H or OCH3; or R1R2 is -OCH2O-; R3 is H or OH; and R4 is OH or OCH3. These substances have been denominated 'combretastatin A-1, -A-2, -A-3, -B-1, -B-2, -B-3 and -B-4'. preparation containing the substances and methods of treating a host inflicted with a neoplastic growth with the preparation is described.

专利号:US-2007275962-A1
优先权日:2003-09-10
标 题:Heterobicyclic Compounds as Pharmaceutically Active Agents
发明人：KOUL ANIL; KLEBL BERT; MULLER GERHARD; MISSIO ANDREA; SCHWAB WILFRIED; HAFENBRADL DORIS; NEUMANN LARS; SOMMER MARC-NICOLA; MULLER STEFAN; HOPPE EDMUND; FREISLEBEN ACHIM; BACKES ALEXANDER; HARTUNG CHRISTIAN; FELBER BEATRICE; ZECH BIRGIT; ENGKVIST OLA; KERI GYORGY; ORFI LASZLO; BANHEGYI PETER; GREFF ZOLTAN; HORVATH ZOLTAN; VARGA ZOLTAN; MARKO PETER; PATO JANOS; SZABADKAI ISTVAN; SZEKELYHID ZSOLT; WACZEK FRIGYES
权利人:GPC BIOTECH AG
摘要:Described are heterobicyclic compounds such as 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]thiopyran 3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid amides, or benzo[b]thiophene-3-carboxylic acid amides and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of various diseases such as infectious diseases, including mycobacteriainduced infections and opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as compositions containing at least one heterobicyclic compound and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the heterobicyclic compound are disclosed.

专利号:EP-1200395-B1
优先权日:1999-07-28
标 题:Urea derivatives as inhibitors of ccr-3 receptor
发明人：PADIA JANAK; HOCKER MICHAEL D; OHASHI HIROSHI; NISHITOBA TSUYOSHI; SAWA EIJI
权利人:KIRIN BREWERY
摘要:Urea and thiourea derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful urea and thiourea derivatives can be synthesized using liquid and solid phase synthesis protocols.

专利号:US-4709087-A
优先权日:1984-12-28
标题:Process for the synthesis of isocyanates and of isocyanate derivatives

专利号:US-6054464-A
优先权日:1996-02-23
标题:Azabicyclic esters of carbamic acids useful in therapy
发明人：MACOR JOHN; WU EDWIN
权利人:ASTRA AB
摘要:A compound of formula ##STR1## X is O or S; Y is O or S; G and D are independently nitrogen or carbon with the proviso that no more than one of G, D, or E is nitrogen; E is N or C--R 4 ; R 1 is hydrogen or methyl; R 2 is hydrogen or fluoro; R 3 is hydrogen, halogen, C 1 to C 3 alkyl, --OR 5 , --CN, --CONH 2 , --CO 2 R 5 , --NR 5 R 6 or phenyl optionally substituted with one to three of the following substituents: halogen, C 1 to C 3 alkyl, --NO 2 , --CN, or --OCH 3 ; R 4 is hydrogen, halogen, C 1 to C 3 alkyl, --OR 5 , --CN, --CONH 2 , --CO 2 R 5 , --NR 5 R 6 or phenyl optionally substituted with one to three of the following substituents: halogen, C 1 to C 3 alkyl, --NO 2 , --CN, or --OCH 3 ; n or R 2 and R 3 or R 3 and R 4 may together represent a fused phenyl ring optionally substituted with one or two of the following substituents: halogen, C 1 to C 3 alkyl, --NO 2 , --CN, or --OCH 3 ; R 5 and R 6 are independently hydrogen or C 1 to C 3 alkyl; n or an enantiomer thereof, and pharmaceutically acceptable salts thereof, processes for preparing the, compositions containing them, and their use in therapy, especially in the treatment or prophylaxis of psychotic disorders and intellectual impairment disorders, as well as intermediates and use of intermediates in synthesis.