CAS: 191591-43-2; (3-Chloro-4,4,4-Trifluorobut-2-Enyl)Sulfonylbenzene
该化合物是一种有机化合物,其独特的结构特征包括一个用氯和三氟甲基组替代的丁乙烯组,以及一个苯二氟硫酸;该化合物通常具有高热稳定性等特性,而且由于有隔热功能组的存在,对各种化学反应具有抗药性;三氟甲基组有助于其亲和性,能够影响其与生物系统的反作用和互动;此外,氯原子可增强化合物的电益特性,使其在各种合成应用中可能有用;其分子结构表明,在农业化学品或制药中可能应用,而此类功能组可开展具体的生物活动;然而,由于卤化化合物具有潜在的毒性,应当谨慎对待处理和使用;与任何化学品一样,在使用和处置过程中应当遵循适当的安全议定书.
- 英文名称(3-Chloro-4,4,4-Trifluorobut-2-Enyl)Sulfonylbenzene
- 中文名称3-氯-4,4,4-三氟-2-丁烯基 苯基 砜
- 其它别名Benzene,[(3-chloro-4,4,4-trifluoro-2-butenyl)sulfonyl]- (9CI)
- CAS编号191591-43-2
- MFCD编号:MFCD01318134
- 分子式:C10H8ClF3O2S分子量:284.68
- 产品CID: 970760
- 产品分类化学试剂 → 有机试剂 → 砜,亚砜类化合物
MSDS等安全信息
合成工艺路线路线简述
📜Sodium Benzenesulfonate,2,4-Dichloro-1,1,1-Trifluoro-2-Butene 以 甲醇 用作溶剂,化学反应 17.0H,以65%的收率获得3-氯-4,4,4-三氟-2-丁烯基 苯基 砜
参考文献:1,3-Dichloro-4,4,4-Trifluorobut-2-Ene As A 4-Carbon Building Block Containing A Trifluoromethyl Group
标题:1,3-Dichloro-4,4,4-Trifluorobut-2-Ene As A 4-Carbon Building Block Containing A Trifluoromethyl Group
摘要:The Preparation,Isomerization,And Utility Of Cf3Ccl=chch2Cl As A 4-Carbon Reagent For The Incorporation Of A Trifluoromethyl Group Is Described. The Regiochemistry Observed For Charged Intermediates Derived From Cf3Ccl=chch2Cl Was Consistent With Mndo Calculated Partial Charges At C-1 And C-3. The Anion-Stabilizing And Cation-Destabilizing Effects Of The Trifluoromethyl Group Were Dominant.
Doi:10.1016/s0022-1139(96)03513-0
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902200000-苯
2903210000-氯乙烯 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-6013838-A
优先权日:1998-01-27
标题:Chemical intermediates bearing a trifluoromethyl group
发明人：VAN DER PUY MICHAEL
权利人:ALLIED SIGNAL INC
摘要:Novel trifluoromethylated intermediates are provided which are useful in synthesizing trifluoromethylated organic compounds. Specifically, compounds of the formula CF 3 CR are provided, wherein R is (Cl)â•?CHCH 2 SO 2 Ph, (Cl)â•?CHCH 2 CH 2 C(â•?O)CH 3 , (Cl)â•?CHCH 2 CH(COCH 3 ) 2 , (Cl)â•?CHCH 2 NR'R' or Hâ•?CHCHâ•?NR'; R' and R' are the same or different and are selected from the group consisting of hydrogen, unsubstituted or substituted C 1 to C 6 straight chain or branched alkyl, unsubstituted or substituted C 3 to C 7 cycloalkyl, unsubstituted or substituted C 2 to C 12 alkenyl, a benzyl group unsubstituted or substituted with R'', or a phenyl group unsubstituted or substituted with R''; or R' and R' taken together form a five- or six-membered ring; and R'' is an unsubstituted or substituted C 1 to C 6 straight chain or branched alkyl, an unsubstituted or substituted C 1 to C 6 alkoxy, an unsubstituted or substituted C 1 to C 6 thioakyl, a cyano, a halogen, or a C 1 to C 2 dialkylamino group; with the proviso that when the alkyl, cycloalkyl or alkenyl of R' or R' or the alkyl, alkoxy or thioalkyl of R'' is substituted, it may be substituted with any group compatible with amine functionality. The novel compounds are versatile intermediates for the synthesis of a wide variety of trifluoromethylated organic compounds, which have found great utility as pharmaceuticals, agricultural chemicals, and materials such as liquid crystals.
