CAS: 1617-53-4; 8-(5-(5,7-Dihydroxy-4-Oxo-4H-Chromen-2-yl)-2-Hydroxyphenyl)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4H-Chromen-4-One

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CAS号48236-96-0 穗花杉双黄酮 | CAS号17482-37-0 amentoflavone h... | CAS号49620-13-5 罗波斯塔双黄酮

四氢阿曼托黄素; 穗花杉双黄酮置于硫酸,碘体系中,用 二甲基亚砜 用作溶剂,化学反应 1.0H,反应生成穗花杉双黄酮
参考文献:Tetrahydroamentoflavone From Nuts Of Semecarpus Prainii
标题:Tetrahydroamentoflavone From Nuts Of Semecarpus Prainii
摘要:
Doi:10.1016/0031-9422(81)83061-0

专利信息

专利号:US-2002165207-A1
优先权日:2001-05-02
标题 :Compositions and methods for the treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD
摘要:Compositions and a method for the treatment of diabetic neuropathy is disclosed. The compositions comprise a mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant, optionally formulated in a pharmaceutically acceptable carrier. This combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In addition, the compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is administered on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms of diabetic neuropathy, as well as at least some recovery of the damaged nerve tissues.

专利号:US-7914823-B2
优先权日:2000-12-21
标题 :Method and composition for the topical treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD ALLEN
权利人:PROPHASE LABS INC
摘要:A method and composition for the treatment of diabetic neuropathy is disclosed. The composition comprises a cold compounded mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant formulated in a pharmaceutically acceptable carrier. It has been found that this combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In view of the consensus in the art that effective combinations of various active agents have not been demonstrated to be effective for the treatment of diabetic neuropathy, the present invention provides a surprising and unexpected effect. In addition, the topical compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the topical administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is topically administered to the areas of the body that have been adversely affected by the diabetic neuropathy on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms and at least some recovery of the damaged nerve tissues.

专利号:US-9296717-B2
优先权日:2009-08-19
标 题 :Synthesis of C-3 coupled biflavonoids and C-3 coupled biflavonoid analogues
发明人：VAN DER WESTHUIZEN JAN HENDRIK; BONNET SUSANNA LUCIA; ACHILONU MATHEW; SISA MIROSLAV
权利人:VAN DER WESTHUIZEN JAN HENDRIK; BONNET SUSANNA LUCIA; ACHILONU MATHEW; SISA MIROSLAV; UNIV FREE STATE ZA
摘要:The preparation of C-3 coupled biflavonoids and C-3 coupled biflavonoid analogs occurs from flavan-3-ones that are contacted with a compound having a nucleophilic aromatic moiety, in the presence of a Lewis acid where an intermediate compound is formed with a C-3 hydroxy group. A flavan-3-ol can be converted to a flavan-3-one as required. The intermediate compound is dehydrated to a flavene with a C-3-C-4 double bond. The flavene compound undergoes hydroboration-oxidation hydration to introduce a C-4 hydroxy group that can be oxidized to an oxo group or can be dihydroxylation to introduce hydroxy groups at the C-4 and C-3 carbons and dehydrated to a biflavonoid or biflavonoid analog having an oxo group at its C-4 carbon and substituted by the selected nucleophilic aromatic moiety on its C-3 carbon.

专利号:CN-110184247-B
优先权日:2019-05-09
标 题:Melatonin synthesis gene MsASMT in alfalfa and its application in regulating the synthesis of melatonin and flavonoids in plants

专利号:US-2024010757-A1
优先权日:2022-07-08
标题:Process of fractionation and recovery of flavonoids, terpenes and prebiotic fiber containing polysaccharides from plant material, use of plant material, and flavonoids, terpenes and prebiotical fiber containing polysaccharides
发明人：DA SILVA SOARES FILIPE; GUERRA FRANCISCO JOSÉ; LOPES OTHNIEL RODRIGUES
权利人:FIBER CITRUS IND E COMERCIO LTDA
摘要:Example embodiments relate to a process for fractionation and total recovery of flavonoids, terpenes and polysaccharides from the bark of a vegetable material, such as citrus peel, without generating effluents. Example embodiments also refer to flavonoids, terpenes and polysaccharides obtained by the process and their use in various applications in the food, cosmetic, pharmaceutical or chemical areas. The process allows the total recovery of the flavonoids, terpenes and polysaccharides components without the use of extreme pH and temperature conditions and without generating effluents, providing a clean and sustainable process, since citrus peel is used as a material for starting point and includes steps of acid synthesis by a metal ion sequestration mechanism.

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人：NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.