CAS: 122-07-6; 2,2-Dimethoxy-N-Methylethanamine

上下游产品

CAS号7252-83-7 溴代乙醛缩二甲醇 | CAS号74-89-5 氨基甲烷 | CAS号51471-08-0 1,5,6,7-四氢-1-甲基... | CAS号6646-51-1 2-氨基-1-甲基咪唑 | CAS号80376-82-5 N-(2,2-Diphenyl... | CAS号69184-36-7 2-CHLORO-N-(2,2...

(2,2-Dimethoxyethyl)(Methyl)Carbamic Acid Tert-Butyl Ester置于三氟乙酸体系中,用 二氯甲烷 用作溶剂,化学反应 16.0H,反应生成甲氨基乙醛缩二甲醇
参考文献:由三氟乙醇介导的未活化的酯衍生物的酰胺化†
标题:由三氟乙醇介导的未活化的酯衍生物的酰胺化†
摘要:已经开发了由2,2,2-三氟乙醇介导的催化酰胺化方案,可促进未活化的酯和胺的缩合,同时提供仲酰胺和叔酰胺.描述了该方法的完整范围和局限性,以及具有挑战性的底物(如无环仲胺和手性酯)的修饰条件,并保留了手性完整性.
Doi:10.1039/c7Ob00593H

专利信息

专利号:US-5670666-A
优先权日:1993-09-27
标题:Process for preparing intermediates for the synthesis of D1 antagonists
发明人：HOU DONALD; DRAPER RICHARD W; LEE GARY M; MAS JANET L
权利人:SCHERING CORP
摘要:Disclosed are a process and intermediates of the formulae ##STR1## wherein X - is halide, BF 4 - , R 3 SO 3 - , wherein R 3 is C 1 -C 6 alkyl, CF 3 , C 1 -C 6 alkylphenyl or phenyl, and Q is a group of the formula ##STR2## wherein R is C 1 -C 6 alkyl; useful for preparing benzazepine intermediates of the formula ##STR3## These benzazepine intermediates are useful for preparing benzazepines having activity as selective D1 receptor antagonists.

专利号:US-7186709-B2
优先权日:2002-08-27
标 题:Dihydropyrancarboxamides and uses thereof
发明人：SCHREIBER STUART L; STAVENGER ROBERT A; MITCHISON TIMOTHY J; MALIGA ZOLTAN
权利人:HARVARD COLLEGE
摘要:The present invention provides novel dihydropyrancarboxamide compounds of formula (I): n nand collections of these compounds, and provides methods for the synthesis of these compounds; wherein R 1 –R 6 are as defined herein. Additionally, the present invention provides pharmaceutical compositions and methods for treating disorders such as proliferative diseases, and cancer, to name a few.

专利号:US-9035061-B2
优先权日:2010-07-13
标题:Process for preparing a biphenyl-2-ylcarbamic acid
发明人：COLSON PIERRE-JEAN
权利人:COLSON PIERRE-JEAN; THERAVANCE BIOPHARMA R & D IP LLC
摘要:The invention provides a process of preparing an intermediate useful in the synthesis of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and a process of preparing a crystalline freebase of the ester.

专利号:US-7385064-B1
优先权日:2005-11-30
标题 :Catalysts for use in enantioselective synthesis
发明人：DAVIES HUW M L; REDDY RAVISEKHARA P
权利人:UNIV NEW YORK STATE RES FOUND
摘要:Disclosed are compounds having the following formula: n nin which Z 11 is selected from a substituted or unsubstituted saturated adamantyl or other polycyclic group and a substituted or unsubstituted branched acyclic group containing at least 5 carbon atoms at least one of which is a tertiary carbon; and in which Z 12 is a cyclic imide. Methods of using these compounds as chiral catalysts for carbenoid reactions and for enantioselective C—H aminations are also described.

专利号:WO-9509156-A1
优先权日:1993-09-27
标 题 :Processes and intermediates for the enantiospecific synthesis of benzo(d)naphth(2.1-b)azepines

专利号:US-9351954-B2
优先权日:2009-12-04
标 题:Multicyclic compounds and methods of use thereof
发明人：SHAO LIMING; CAMPBELL JOHN EMMERSON; HEWITT MICHAEL CHARLES; CAMPBELL UNA; HANANIA TALEEN G
权利人:SUNOVION PHARMACEUTICALS INC; PGI DRUG DISCOVERY LLC
摘要:Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. For example, disclosed herein are compounds having formula (IIa) shown below, or a pharmaceutically acceptable salt or stereoisomer thereof, wherein the variables are defined herein. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.