CAS: 103889-37-8; 1-Chloro-3-Fluoro-2-(Trifluoromethyl)Benzene

该化合物是一种芳香化合物,其特点是存在一个苯环,代之以氯原子,氟原子和三个三氟甲基组;该化合物一般没有色素,可粉黄,具有独特的气味;因其稳定性和耐降解性而闻名,在各种应用中有用,包括作为一种溶剂和其他化合物的合成;多种电阴性替代成分的存在,助长了其极地性质,影响其在不同溶剂中的溶解性;此外,2-Chroloo-6-氟-氟化硫化物展览具有卤化芳烃化合物的典型特性,例如潜在的环境持久性和生物蓄积性;安全数据表明,应谨慎处理,因为它可能对接触健康造成危害.

英文名称1-Chloro-3-Fluoro-2-(Trifluoromethyl)Benzene
中文名称1-氯-3-氟-2-(三氟甲基)苯
IUPAC名称1-chloro-3-fluoro-2-(trifluoromethyl)benzene
其它别名1-氯-3-氟-2-三氟甲苯; 2-Chloro-6-Fluorobenzotrifluoride
CAS编号103889-37-8
MFCD编号:MFCD03412198
分子式:C7H3ClF4
分子量:198.55
产品CID: 75064
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: ILUCOEVDXAZECW-UHFFFAOYSA-N
InChI=1S/C7H3ClF4/c8-4-2-1-3-5(9)6(4)7(10,11)12/h1-3H…
计算化学: 氢键受体数*氢键供体数0.0可旋转键数0.0

相似化合物

1261535-74-3 1099597-70-2 1099597-48-4

MSDS等安全信息

GHS符号GHS05,GHS07
警示词Danger
危险描述H302-H314
防范说明P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
危险等级8
UN编号1760.0
危险品标志Xi
风险等级Irritant
包装等级Ⅲ
安全声明26-36/37/39
危险类别码36/37/38

合成工艺路线路线简述

专利信息

专利号:US-4668830-A
优先权日:1984-12-26
标题 :Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group. A compound containing a carbonyl group, preferbly an acid, acid halide, amide, ketone or any compound containing a perhaloalkylcarbonyl moiety is placed, in anhydrous liquid hydrofluoric acid, in contact with boron trifluoride in a quantity such that the absolute pressure of boron trifluoride in the reaction system is at least one bar for a time sufficient to convert the carbonyl group to a difluormethylene or trifluoromethyl group. n The compounds obtained are useful as synthesis intermediates in the pharmaceutical, plant-protection and dye industries, as anesthetics or as heat-transfer and lubricating fluids.