CAS: 90223-31-7; 5-Amino-2-Methyl-3-Nitrobenzamide

相似化合物

40637-78-3 13138-53-9 148-01-6

上下游产品

zoalene

📜二硝托胺置于palladium On Activated Charcoal,环己烯体系中,用 乙醇 作为反应溶剂,化学反应生成 5-氨基-2-甲基-3-硝基苯甲酰胺,3-氨基-2-甲基-5-硝基苯甲酰胺
参考文献:Chemical Reduction Of Zoalene To Anot For Use In Zoalene Residue Studies
标题:Chemical Reduction Of Zoalene To Anot For Use In Zoalene Residue Studies
摘要:A Novel Chemical Synthesis And Purification Scheme To Produce Anot (3-Amino-5-Nitro-O-Toluamide) Was Developed To Yield An Analytical Standard Grade Material For Zoalene Residue Investigations. An Original Conversion Of Zoalene (3,5-Dinitro-O-Toluamide) To Anot Was Developed. Several Literature References Were Available For The Partial Reduction Of Dinitro Aryl Compounds,But None Detailed The Conversion Of Zoalene To Anot. A Chemical Synthesis Was Chosen Over A Biological Synthesis Due To The Latter'S Complex Reaction Matrix,Difficult Recovery,And Low Batch Yields. Using General Partial Reduction Of Dinitro Aryl Schemes,It Was Found That 10% Palladium On Carbon Coupled To A Cyclohexene Reducing Agent Provided An Optimum Anot Yield. Chromatographic Techniques Were Utilized To Isolate Anot From The Product Mixture And To Purify It To A Standard Grade Material (>99% Pure). The Chemically Synthesized Anot Product Was Characterized Using Colorimetric,Tlc,Ftir,NMR,And Lc/ms Techniques.
DOI:10.1021/jf9802068