CAS: 77732-09-3; Oxadixyl

该化合物是能够抑制各种真菌病原体的生长,使其有效地保护作物免受疾病之害;Oxadixyl通常用于一系列作物,包括蔬菜和水果,以提高产量和质量;该化合物以其系统性行动而著称,允许植物吸收该化合物,并保护其不受体内影响;就物理特性而言,Oxadixyl一般是白到白的晶状固体,在水和有机溶剂中具有中度溶解性;其行动方式涉及破坏真菌细胞壁合成,最终导致细胞死亡;虽然其有效,但Oxadixyl的使用与许多农药一样,必须接受监管审查,以确保环境安全,并尽可能减少对非目标生物的潜在影响;就物理特性而言,正确处理和应用对于最大限度地发挥其功效,同时尽量减少风险至关重要.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    📜2-Chloroethyl 2-(Methoxyacetyl)-2-(2,6-Dimethylphenyl)-Hydrazinecarboxylate 以 甲苯,Mineral Oil 作为反应溶剂,化学反应生成 恶霜灵
    参考文献:Fungicides
    标题:Fungicides
    摘要:本发明提供了一种杀菌组合物,其包括一种n-氨基-2-氧代-3-噁唑烷衍生物(组分a),例如2-甲氧基-N-(2,6-二甲基苯基)-N-(2-氧代-3-噁唑烷基)-乙酰胺,以及一种从铜杀菌剂,福尔马林,卡普坦,甲基硫菌灵或甲基托布津中选择的组分(b).本发明的另一个目的是使用组分(a)和组分(b)的杀菌有效量来对抗植物,种子或土壤中的植物病原真菌的方法.

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:US-2016073631-A1
    优先权日:2013-03-04
    标 题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:US-9233920-B2
    优先权日:2010-06-11
    标题 :Process for the preparation of dihydropyrrole derivatives
    发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
    权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
    摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    专利号:US-6600029-B1
    优先权日:1995-12-19
    标题:Metabolic engineering of polyhydroxyalkanoate monomer synthases
    发明人:SHERMAN DAVID H; WILLIAMS MARK D; XUE YONGQUAN
    权利人:UNIV MINNESOTA
    摘要:A novel pathway for the synthesis of polyhydroxyalkanoate is provided. A method of synthesizing a recombinant polyhydroxyalkanoate monomer synthase is also provided. These recombinant polyhydroxyalknoate synthases are derived from multifunctional fatty acid synthases or polyketide synthases and generate hydroxyacyl acids capable of polymerization by a polyhydroxyalknoate synthase.

    专利号:US-5614551-A
    优先权日:1994-01-24
    标题:Inhibitors of fatty acid synthesis as antimicrobial agents
    发明人:DICK JAMES D; KUHAJDA FRANCIS P
    权利人:UNIV JOHNS HOPKINS
    摘要:Fatty acid synthase (FAS) is overexpressed by certain infectious organisms that are resistant to most currently available antibiotics. Contrarywise, little FAS expression is identified in patient tissues. Inhibition of fatty acid synthesis is thus selectively toxic to invasive cells, while patient cells with low FAS activity are resistant. This invention provides a method of treating septic patients where fatty acid synthesis by invading cells is inhibited with resultant interruption of the disease process.

    专利号:US-10906880-B2
    优先权日:2016-01-26
    标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
    发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
    权利人:UNIV NANKAI
    摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Ruan W, Peng Y, Liao R, Man Y, Tai Y, Tam NF, Zhang L, Dai Y, Yang Y. Removal, transformation and ecological risk assessment of pesticide in rural wastewater by field-scale horizontal flow constructed wetlands of treated effluent. Water Res. 2024 Jun 1;256:121568. doi: 10.1016/j.watres.2024.121568. Epub 2024 Apr 2.
    13:908879. doi: 10.3389/fmicb.2022.908879.
    3: Cha J, Hong S, Gwak J, Kim M, Lee J, Kim T, Han GM, Hong SH, Hur J, Giesy JP, Khim JS. Identification of novel polar aryl hydrocarbon receptor agonists accumulated in liver of black-tailed gulls in Korea using advanced effect- directed analysis. J Hazard Mater. 2022 May 5;429:128305. doi: 10.1016/j.jhazmat.2022.128305. Epub 2022 Jan 19.

    合成参考文献


    摘要:Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan., 13(639), 1988
    摘要:S132 | UJIGCAPCICCS | A GC-APCI-IMS-HRMS CCS Library from Izquierdo-Sandoval et al. (2022) | DOI:10.5281/zenodo.15831151
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