CAS: 33159-27-2; (1R,4As,10Ar)-7-Isopropyl-1,4A-Dimethyl-6-Sulfo-1,2,3,4,4A,9,10,10A-Octahydrophenanthrene-1-Carboxylic Acid
该化合物是胃溃疡和其他胃肠紊乱的治疗,被归类为胃保护剂,通过增强胃内衬的肌肉防御机制发挥作用;Ecabet工作,其促进粘液和双碳酸的分泌,这有助于中和气酸,保护上皮细胞免受损害;此外,它可能具有有助于其保护作用的抗炎特性;该化合物一般是口服的,在胃肠道内吸收良好;其安全性能一般比较有利,其副作用在发生时相对少见和轻微;与任何制药剂一样,必须在医疗监督下使用Ecabet,以确保适当的剂量,并监测与其他药物的任何潜在互动.
- 英文名称(1R,4As,10Ar)-7-Isopropyl-1,4A-Dimethyl-6-Sulfo-1,2,3,4,4A,9,10,10A-Octahydrophenanthrene-1-Carboxylic Acid
- 中文名称依卡倍特
- IUPAC名称(1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-6-sulfo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
- 其它别名12-Sulfodehydroabietic Acid ; 13-Isopropyl-12-Sulfopodocarpa-8,11,13-Trien-15-Oic Acid
- CAS编号33159-27-2
- MFCD编号:MFCD11044526
- FDA UNII编号:2K02669KWP
- 分子式:C20H28O5S分子量:380.51
- 产品CID: 1325430
- 同类组份化合物CAS33159-27-2 (free base)86408-72-2 (sodium)219773-47-4 (sodium hydrate)219773-47-4 (sodium pentahydrate)
- 产品分类有机原料 → 脂质和类脂质分子 → 异戊烯醇脂质
物理性质
上下游产品
CAS号1740-19-8 脱氢枞酸； 脱氢松香酸 | CAS号514-10-3 松香酸 | CAS号1740-19-8 脱氢枞酸； 脱氢松香酸合成工艺路线路线简述
📜脂松香置于硫酸体系中,化学反应生成 依卡倍特
参考文献:The Composition Of So-Called Pyroabietic Acid Prepared Without Catalyst
标题:The Composition Of So-Called Pyroabietic Acid Prepared Without Catalyst
摘要:
DOI:10.1021/ja01871A009
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905121000-正丙醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
专利号:CN-116903498-A
优先权日:2023-06-06
标 题 :A kind of synthesis method of ecabet sodium
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Wang Y, Wang B, Lv ZF, Yang Y, Wang F, Wang H, Chen S, Xie Y, Zhou X. Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Helicobacter. 2014 Oct;19(5):372-81. doi: 10.1111/hel.12136. Epub 2014 May 14. 60 Suppl
2:711-6. Japanese. 345(2):193-8. doi: 10.1016/s0014-2999(97)01622-1. 25(7):1182-4. doi: 10.1111/j.1440-1746.2010.06339.x. 288(2):G300-7. doi: 10.1152/ajpgi.00274.2004. Epub 2004 Sep 30. 13(5):687-94. doi: 10.1046/j.1365-2036.1999.00502.x. 15(2):90-4. doi: 10.1007/s10787-006-1538-0. 19(2):640-645. doi: 10.1166/jnn.2019.15961.
89:1176-83. doi: 10.1016/j.freeradbiomed.2015.11.007. Epub 2015 Nov 10. 57(6):799-805. doi: 10.1211/0022357056271. 36(3):153-7. doi: 10.1007/s005350170122. 60 Suppl
合成参考文献
参考文献:10.1023/a:1018885005109
摘要:Kinoshita M, Tamaki H. Possible Mechanism of Increase in Gastric Mucosal PGE2 and PGI2 Generation Induced by Ecabet Sodium, a Novel Gastroprotective Agent. Digestive Diseases and Sciences. 1997 Jan;42(1):83–90. doi: 10.1023/a:1018885005109.
参考文献:10.2174/0929867023369853
摘要:Amtul Z, Rahman AU, Siddiqui RA, Choudhary MI. Chemistry and mechanism of urease inhibition. Curr Med Chem. 2002 Jul;9(14):1323–48. doi: 10.2174/0929867023369853.
📝 需求与反馈
尽可能描述清楚需求与问题信息
