欧盟法规
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CAS号66601-71-6 anthracene-2-su... | CAS号131-08-8 蒽醌-2-磺酸钠 | CAS号2381-23-9 9,10-二氧代-9,10-二... | CAS号90590-00-4 anthracene-2-thiol📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于三氯氧磷,三氯化磷体系中,化学反应生成2-蒽磺酰氯
参考文献:Woroshzow; Koslow,Zhurnal Obshchei Khimii,1937,Vol. 7,P. 739,742
标题:Woroshzow; Koslow,Zhurnal Obshchei Khimii,1937,Vol. 7,P. 739,742
专利信息
专利号:US-2021246476-A1
优先权日:2020-01-31
标 题:Biosynthesis of preparing nicotinamide mononucleotide and derivatives thereof
发明人:ZHANG YI HENG PERCIVAL
权利人:ZHANG YI HENG PERCIVAL
摘要:A method of making nicotinamide mononucleotide (NMN), nicotinamide mononucleotide derivatives, or mixtures thereof is disclosed. The method involves the in vitro artificial enzymatic pathways comprised: the generation of alpha-D-ribose-1-phosphate from numerous substrates followed by the synthesis of nicotinamide mononucleotide catalyzed by nicotinamide riboside phosphorylase and nicotinamide riboside kinase or the generation of 5-phospho-alpha-D-ribose-1-diphosphate from nucleotides followed by the synthesis of nicotinamide mononucleotide catalyzed by nicotinamide phosphoribosyltransferase. The multiple enzymes were reconstituted in one pot, wherein in-situ removal of byproducts that can be converted to other non-inhibitory chemicals with supplementary enzymes push the overall biotransformation toward the synthesis of nicotinamide mononucleotide. Furthermore, nicotinamide mononucleotide can be converted to its derivatives—nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate.
专利号:US-5419966-A
优先权日:1991-06-10
标 题 :Solid support for synthesis of 3'-tailed oligonucleotides
发明人:REED MICHAEL W; MEYER JR RICH B; PETRIE CHARLES R; TABONE JOHN C
权利人:MICROPROBE CORP
摘要:A solid support for oligonucleotide synthesis has the structure where CPG represents a controlled pore glass matrix, the wavy line represents a carbon chain covalently linking the NH group with the controlled pore glass matrix, X is 2,2'-dimethoxytrityl or H, and R is alkyl, aryl, arylalkyl, heteroalkyl, or heteroaryl. The dimethoxytrityl group is removed from the solid support by treatment with acid, and the oligonucleotide is built, step-by-step in a conventional synthesizer after attachment of the 3' end of the first oligonucleotide unit to the hydroxyl function connected to the R group.
专利号:EP-0383803-B1
优先权日:1987-10-28
标题 :Oligonucleotide-polyamide conjugates
发明人:HARALAMBIDIS JIM; TREGEAR GEOFFREY WILLIAM
权利人:HOWARD FLOREY INST OF
摘要:Oligonucleotide-polyamide conjugates of the formula X-L-Y, where X is a polyamide, Y is an oligonucleotide, and L is a linker which forms a covalent bond with the amino-terminus of the polyamide X and the 3' phosphate group of the oligonucleotide Y. Conjugates may be synthesized by assembling a polyamide on a solid support matrix, adding a suitable linker molecule, followed by synthesis of the oligonucleotide. Methods for detecting specific polynucleotides with oligonucleotide-polyamide conjugates are also described.
专利号:US-5525465-A
优先权日:1987-10-28
标 题:Oligonucleotide-polyamide conjugates and methods of production and applications of the same
发明人:HARALAMBIDIS JIM; TREGEAR GEOFFREY W
权利人:FLOREY HOWARD INST
摘要:Oligonucleotide-polyamide conjugates of the formula X--L--Y, where X is a polyamide, Y is an oligonucleotide, and L is a linker which forms a covalent bond with the amino-terminus of the polyamide X and the 3' phosphate group of the oligonucleotide Y. Conjugates may be synthesized by assembling a polyamide on a solid support matrix, adding a suitable linker molecule, followed by synthesis of the oligonucleotide. Methods for detecting specific polynucleotides with oligonucleotide-polyamide conjugates are also described.
专利号:WO-9203464-A1
优先权日:1990-08-28
标题 :Solid support synthesis of 3'-tailed oligonucleotides via a linking molecule
专利号:CN-112877386-A
优先权日:2021-01-28
标 题:A kind of method based on enzymatic synthesis of nicotinamide mononucleotide