CAS: 14898-79-4; (R)-(-)-2-Butanol

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4221-99-2 32970-45-9 584-02-1

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CAS号78-93-3 甲乙酮 | CAS号78-92-2 仲丁醇 | CAS号73255-17-1 (R)-((sec-butox... | CAS号590-18-1 顺-2-丁烯 | CAS号78-94-4 丁烯酮 | CAS号42969-65-3 (R)-(+)-3-丁炔-2-醇 | CAS号15448-47-2 (R)-环氧丙烷 | CAS号624-64-6 反-2-丁烯 | CAS号513-48-4 碘代仲丁烷 | CAS号78-93-3 甲乙酮 | CAS号78-76-2 溴代仲丁烷 | CAS号5787-33-7 [R,(-)]-2-Bromo... | CAS号4141-50-8 Phosphine oxide... | CAS号61530-30-1 (R)-4-甲基苯磺酸仲丁酯

反-2-丁烯置于双氧水体系中,化学反应生成(R)-(-)-2-丁醇
参考文献:Hydroboration. 85. Synthesis And Hydroboration Of (-)-2-Phenylapopinene. Comparison Of Mono(2-Phenylapoisopinocampheyl)Borane With Its 2-Methyl And 2-Ethyl Analogs For The Chiral Hydroboration Of Representative Alkenes
标题:Hydroboration. 85. Synthesis And Hydroboration Of (-)-2-Phenylapopinene. Comparison Of Mono(2-Phenylapoisopinocampheyl)Borane With Its 2-Methyl And 2-Ethyl Analogs For The Chiral Hydroboration Of Representative Alkenes
摘要:
Doi:10.1021/jo00291A021

专利信息

专利号:WO-9006311-A1
优先权日:1988-11-29
标 题 :Synthesis of (-)-swainsonine and intermediate compounds employed in such synthesis
发明人：CHA JIN KUN; BENNETT RICHARD BERNARD III
权利人:UNIV VANDERBILT
摘要:A method of synthesizing swainsonine and its analogues employing a unique intermediate imine and a unique intermediate enamide.

专利号:US-2018111938-A1
优先权日:2015-05-05
标 题:Synthesis of Intermediates Used in the Manufacture of Anti-HIV Agents
发明人：PRADHAN BRAJA SUNDAR; AMARNATH KOMMIREDDY; VEMPALA NARESH; RAHMAN MD ATAUR
权利人:CBZ INVEST LTD
摘要:The present invention relates to a process of preparing intermediates of Formula (I). The process comprises of reacting compound of Formula (III) with compound of Formula (V) in the presence of a solvent selected from an alcohol, ether or water to form compound of Formula (I) wherein, R 1 is selected from —NH 2 , Cl, Br, NHCOR″, wherein R″ is alkyl, aryl, Schiff's base of formula Nâ•?CHR′, wherein R′ is alkyl or aryl; R 2 is selected from H, alkyl; R 3 and R 4 , each independently is H; R 5 and R 6 , each independently is H, alkyl; R 7 is H, alkyl; and R 8 is H, alkyl.

专利号:US-8653282-B2
优先权日:2007-10-18
标 题:Preparation of dihydrothieno [3,2-D] pyrimidines and intermediates used therein
发明人：FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G
权利人:FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G; BOEHRINGER INGELHEIM INT
摘要:The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO 2 , preferably SO, and wherein R A , R 1 , R 2 , R 3 , R 4 and R 5 have the meanings given in the description. The methods according to this invention are more suitable for large-scale synthesis of said compounds than prior methods because the new synthetic process avoids distillation and chromatographic purification between steps and results in a higher overall yield of the desired product.

专利号:US-6255092-B1
优先权日:1993-09-24
标题:Stereospecific alcohol dehydrogenase isolated from Candida parapsilosis, amino acid and DNA sequences therefor, and method of preparation thereof
发明人：KOJIMA TOMOKO; YAMAMOTO HIROAKI; KAWADA NAOKI; MATSUYAMA AKINOBU
权利人:DAICEL CHEM
摘要:The present invention provides a novel secondary alcohol dehydrogenase useful for the synthesis of optically active alcohol and DNA encoding said enzyme. A microorganism belonging to genus Candida was found to produce a novel secondary alcohol dehydrogenase with a high stereochemical specificity. Using said enzyme, optically active alcohols were prepared, and by cloning of DNA encoding said enzyme, the base sequence of said DNA was determined. By providing a novel secondary alcohol dehydrogenase with a high stereochemical specificity and the gene encoding said enzyme, an efficient production of optically active alcohols became possible.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6906056-B2
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
权利人:LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.