CAS: 13492-01-8; Trans-2-Phenylcyclopropanamine Hemisulfate

上下游产品

(1SR,2SR)-2-phenylcyclopropanecarbonyl chloride (E)-3-phenylacrylic acid trans-2-phenylcyclopropane-1-carboxylic acidmethyl 7-(4-((2-phenylcyclopropyl)carbamoyl)phenoxy)-6-cyano-3,4-dihydro-2H-chromene-4-carboxylate tert-butyl (trans-2-phenylcyclopropyl)carbamate 2-phenylcyclopropylamine N-methyl-trans-2-phenylcyclopropylamine hydr°Chloride

专利信息

专利号:US-4016204-A
优先权日:1975-10-31
标 题 :Method of synthesis of trans-2-phenylcyclopropylamine
发明人：RAJADHYAKSHA VITHAL JAGANNATH
权利人:NELSON RES & DEV
摘要:An improved method of synthesis of trans-2-phenylcyclopropylamine wherein the improvement comprises isomerizing an intermediate ester, namely, cis,trans-ethyl-2-phenylcyclopropanecarboxylate, by reacting said ester with anhydrous sodium ethoxide, to form a reaction product containing not more than about 5 percent cis ester and further reacting said resultant product to form trans-2-phenylcyclopropylamine.

专利号:EP-3617181-A1
优先权日:2018-08-30
标题:Synthesis of trans-2-phenylcyclopropylamine or a salt or solvate thereof
发明人：BREUNING ALEXANDER; LIMMERT MICHAEL; DELLING AXEL; HOFMEIER HARALD; HULTSCH JANA; MICKSCH MAIK; SOMMER CHRISTIAN
权利人:AREVIPHARMA GMBH
摘要:The present invention relates to the field of manufacturing trans-2-phenylcyclopropylamine or a salt or solvate thereof, in particular in the form of the sulphate salt. The obtained product, particularly when in the form of the synthesis of trans-2-phenylcyclopropylamine sulphate, is exceptionally pure, substantially free from reactants and reagents that are mutagenic, hazardous or of great concern to the health of humans or the environment.

专利号:IE-44046-B1
优先权日:1975-10-31
标题 :Improved method of synthesis of trans-2-phenylcycloprpylamine

专利号:GB-1561725-A
优先权日:1975-10-31
标题:Method of synthesis of trans-2-phenylcycloproylamine

专利号:US-11459325-B2
优先权日:2018-01-31
标题:Heterocyclic compound
发明人：TANAKA YUTA; OHASHI TOMOHIRO; IKEDA ZENICHI; TANAKA YUTA; PÃœNNER FLORIAN; YAMAMOTO TAKESHI; KAKEGAWA KEIKO; KIKUCHI FUMIAKI; MORISHITA NAO; KASAHARA TAKAHITO; SETO MASAKI; NAKAMURA MINORU; TAKAMI KAZUAKI; MURAKAMI MASATAKA; DAINI MASAKI; MIKAMI SATOSHI; SASAKI MINORU
权利人:TAKEDA PHARMACEUTICALS CO
摘要:The present invention provides a compound having a glucosylceramide lowering action (e.g., promoting glucosylceramide metabolism, inhibition of glucosylceramide synthesis, promoting glucosylceramide catabolism, etc.), which is expected to be useful as an agent for the prophylaxis or treatment of lysosome diseases (e.g., Gaucher's disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like. n The present invention relates to a compound represented by the formula (I): n nwherein each symbol is as described in the specification, or a salt thereof.