CAS: 13057-98-2; 2-(Carboxy(2-Phenylacetamido)Methyl)-5,5-Dimethylthiazolidine-4-Carboxylic Acid

该化合物是苯丙基苯丙胺(Benicillin G)的降解产物,通过β-林丹环的液解裂形成,是研究二硝基苯基新陈代谢和过敏反应,特别是在免疫化学研究中的关键中间体.该化合物对调查二硝基苯基特定抗体和超敏性机制很有价值,因为它在结构上与二硝基苯基衍生的机油管相似.其定义明确的化学特性使它适合在色谱学和质谱学方面的分析标准.苯丙二烯二甲酸还用于稳定研究,以了解不同条件下的二硝基苯基苯基新陈代谢和过敏反应,特别是在免疫化学研究中.该产品通常作为高纯度参考材料供应,用于可靠的实验再生.

结构式图片

上下游产品

benzylpenicillenic acid 6-(2-phenylacetamido)penicillanic acid penicillin G propylamine2-[methoxycarbonyl-(2-phenyl-acetylamino)-methyl]-5,5-dimethyl-thiazolidine-4-carboxylic acid methyl ester benzylpenilloic acid benzylpenicillic acid

合成工艺路线路线简述

    📜青霉素 反应生成苄基青霉酸
    参考文献:Kessler,D. P.;Cushman,M.;Ghebre-Sellassie,I.;Knevel,A. M.;Hem,S. L.,J. Chem. Soc. Perkin Trans.,1983,N 11,1699-1703
    标题:Kessler,D. P.;Cushman,M.;Ghebre-Sellassie,I.;Knevel,A. M.;Hem,S. L.,J. Chem. Soc. Perkin Trans.,1983,N 11,1699-1703

    海关参考信息

    专利信息


    专利号:US-2024401210-A1
    优先权日:2022-04-01
    标题 :Synthesis of transition metal hydroxides, oxides, and nanoparticles thereof
    发明人:YAGHOOBNEJAD ASL HOOMAN
    权利人:ASPEN AEROGELS INC
    摘要:Techniques are disclosed for electrochemical synthesis of rechargeable battery cathode precursor materials using a porous carbon element. The porous carbon element acts as an air cathode to reduce oxygen. Reduced oxygen species may oxidize a transition metal anode, thereby facilitating a room temperature redox reaction with transition metals, including those that are generally resistant to corrosion, such as nickel. The transition metal reaction product(s) may be further processed into rechargeable battery cathode materials without also synthesizing hazardous waste products.

    专利号:WO-2024079704-A1
    优先权日:2022-10-13
    标题 :Synthesis of derivatives of siphonochilone and therapeutic use thereof
    发明人:INVERNIZZI LUKE; MOYO PHANANKOSI; MAHARAJ VINESH
    权利人:UNIV PRETORIA
    摘要:THIS invention relates to the synthesis of derivatives of siphonochilone and therapeutic use thereof in the treatment and prevention of respiratory virus disease, in particular influenza or a coronavirus disease.

    专利号:WO-2022101282-A1
    优先权日:2020-11-13
    标 题 :Synthesis of 25-hydroxy-vitamin d3, 25-hydroxy-7-dehydrocholesterol and analogous alcohols using the beta-proteobacterium thauera aromatica
    发明人:BOLL MATTHIAS; JACOBY CHRISTIAN
    权利人:UNIV FREIBURG ALBERT LUDWIGS
    摘要:The present invention relates to methods using recombinant Thauera aromatica cells to produce oxygen-independent molybdenum-hydroxylases in order to convert vitamin D 3 , 7-dehydrocholesterol and related alkylated compounds into 25-hydroxy-vitamin D 3 , 25- hydroxy-7-dehydrocholesterol and analogous alcohols. The underlying biocatalytic method links the water-dependent hydroxylation of alkyl residues with the nitrate- reducing respiratory chain of the strain as electron acceptor system. In contrast to commonly used methods, the present method does no longer require the artificial regeneration of the electron-carrier.

    专利号:US-4945159-A
    优先权日:1986-12-02
    标 题 :Formation of lactams and other amides under mild conditions by action of cyanogen
    发明人:DAY RICHARD A
    权利人:UNIV CINCINNATI
    摘要:A method for the formation of intramolecular amide bonds by the action of cyanogen, under mild reaction conditions, in the preparation of cyclic amides, including lactams, in biologically active compounds. A compound containing at least one carboxylic acid group and at least one primary or secondary amino group is reacted with cyanogen to form an intramolecular amide bond. The method has utility in the synthesis of B-lactam antibiotics, such as penicillins, cephalosporins, and their derivatives, in enzyme modification, in cyclization of peptides, and in covalent cross-linking of proteins.

    专利号:EP-4573083-A1
    优先权日:2022-10-13
    标题:Synthesis of derivatives of siphonochilone and therapeutic use thereof

    专利号:EP-4392596-A2
    优先权日:2022-04-01
    标 题:Synthesis of transition metal hydroxides, oxides, and nanoparticles thereof

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1038/187939a0
    摘要:LEVINE BB. Degradation of benzylpenicillin at pH 7.5 to D-benzylpenicilloic acid. Nature. 1960 Sep 10;187():939–40. doi: 10.1038/187939a0.
    参考文献:10.1038/187940a0
    摘要:LEVINE BB. Formation of D-penicillamine-cysteine mixed disulphide by reaction of D-benzylpenicilloic acid with cystine. Nature. 1960 Sep 10;187():940–1. doi: 10.1038/187940a0.
    参考文献:10.1084/jem.112.6.1131
    摘要:LEVINE BB. Studies on the mechanism of the formation of the penicillin antigen. I. Delayed allergic cross-reactions among penicillin G and its degradation products. J Exp Med. 1960 Dec 01;112():1131–56.
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