CAS: 116435-77-9; 2-Amino-3-Bromophenol

相似化合物

76361-99-4 38191-34-3 74440-80-5

上下游产品

CAS号5473-01-8 2-溴-6-甲氧基苯胺 | CAS号1431458-17-1 N-(2-bromo-6-hy... | CAS号76361-99-4 3-溴-2-硝基苯酚 | CAS号855836-52-1 2-碘-3-溴苯酚 | CAS号863870-87-5 3-溴-2-氯苯酚

3-溴-2-硝基苯酚置于sodium Hydroxide,Sodium Dithionite体系中,化学反应生成2-氨基-3-溴苯酚
参考文献:Ccclvii.-3-卤代-2-,-4-和-6-氨基苯酚
标题:Ccclvii.-3-卤代-2-,-4-和-6-氨基苯酚
摘要:
Doi:10.1039/jr9280002703

专利信息

专利号:WO-2023072966-A1
优先权日:2021-10-26
标题:Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
发明人：DEAU EMMANUEL; GEORGE PASCAL; MEIJER LAURENT; MIEGE FRÉDÉRIC
权利人:PERHA PHARMACEUTICALS
摘要:The present invention relates to a compound of formula (I) wherein R 1 represents a (C 4 -C 6) alkyl group, a (C 3 -C 8) cycloalkyl group, a bridged (C 6 -C 10 )cycloalkyl group, a fused phenyl group, a substituted phenyl group, a R'-L- group, wherein L is either a single bond or a (C 1 -C 3 )alkanediyl group, and R' represents, a (C 3 -C 8 )heterocycloalkyl group, or a (C 3 -C 8 )heteroaryl group, or a R''-L- group wherein L is a (C 1 -C 3 )alkanediyl group, and R'' is an optionally substituted phenyl group; R 2 is selected from the group consisting of a hydrogen atom and a (C 1 -C 3 )alkyl group; R 5 represents a hydrogen atom, a (C 1 -C 4 )alkyl group or a (C 3 -C 6 )cycloalkyl group or any of its pharmaceutically acceptable salt. The present invention further relates to a composition comprising a compound of formula (I) and a process for manufacturing said compound as well as its synthesis intermediates. It also relates to said compound for use as a medicament, in particular in the treatment and/or prevention of cognitive deficits and neuroinflammation associated with Down syndrome; Alzheimer's disease; dementia; tauopathies; Parkinson's disease; CDKL5 Deficiency Disorder; Phelan-McDermid syndrome; autism; type 1 and type 2 diabetes; abnormal folate and methionine metabolism; osteoarthritis and tendinopathy; Duchenne muscular dystrophy; cancers and leukemias; neuroinflammation, anemia, infections caused by unicellular parasites, viral infections and for regulating body temperature.

专利号:CN-119241459-A
优先权日:2024-09-03
标题:Benzo (A) benzo (B) benzo (A oxazole/benzo Synthesis method of thiazole compound