CAS: 104-52-9; 3-Phenylpropyl Chloride

相似化合物

104-52-9 4830-93-7 622-24-2

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CAS号122-97-4 3-苯丙醇 | CAS号18776-12-0 3-氯-1-苯基丙醇 | CAS号936-59-4 3-氯代苯丙酮 | CAS号3742-75-4 3-Phenylpropyl ... | CAS号866942-16-7 3-phenylpropyl ... | CAS号866942-18-9 3-phenylpropyl ... | CAS号69804-99-5 3-phenylpropano... | CAS号32315-10-9 三光气 | CAS号121-44-8 三乙胺 | CAS号14629-60-8 (Trimethylsilyl... | CAS号100708-34-7 1-(3-iodopropyl... | CAS号329685-40-7 3-苯基-1-丙基硼酸频哪酯 | CAS号55455-92-0 苯基丙基哌嗪 | CAS号143033-85-6 1-[4-(3-chlorop... | CAS号936-59-4 3-氯代苯丙酮 | CAS号496-11-7 茚满 | CAS号4119-41-9 1-碘-3-苯基丙烷 | CAS号2038-62-2 (3-FLUOROPROPYL... | CAS号21763-00-8 (1-溴-3-氯丙基)苯 | CAS号2046-18-6 4-苯基丁腈

3-苯基丙酸置于gallium(III) Trichloride,六甲基二硅氧烷,Copper Dichloride体系中,用 1,2-二氯乙烷 用作溶剂,化学反应 8.0H,以81%的收率获得1-氯-3-苯基丙烷
参考文献:镓催化氯化铜对羧酸的还原氯化反应
标题:镓催化氯化铜对羧酸的还原氯化反应
摘要:本文描述了在氢硅氧烷存在下,使用氯化铜(II)通过镓(III)催化的还原直接氯化羧酸.在该还原氯化过程中,Cucl 2的抗衡阴离子起氯化物源的作用.
Doi:10.1021/jo501912V

专利信息

专利号:US-2023312617-A1
优先权日:2020-07-25
标题 :Process for synthesis of organosilicon compounds from halosilanes
发明人：DOLAI SUKANTA; BHAT SHREEDHAR; TARAFDAR GOURAV
权利人:MOMENTIVE PERFORMANCE MAT INC
摘要:A process for synthesis of an organosilicon compound is provided herein. Also, novel organosilicon compounds prepared by the present process is provided herein. The process comprises the reaction of a halosilane with an organofunctional alkyl halide in the presence of a metal catalyst, a promoter, and an optional co-catalyst. The process provides an efficient synthetic route to produce organosilicon compounds. The process also allows synthesis of organosilicon compounds with a plurality of different functional groups.

专利号:US-7250510-B2
优先权日:2005-08-24
标 题:Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations
发明人：ORGAN MICHAEL G; O'BRIEN CHRISTOPHER J; KANTCHEV ASSAM ERIC B
权利人:TOTAL SYNTHESIS LTD
摘要:The present invention relates to catalysts of transition metal complexes of N-heterocyclic carbenes, their methods of preparation and their use in chemical synthesis. The synthesis, ease-of-use, and activity of the compounds of the present invention are substantial improvements over in situ catalyst generation. Further, the transition metal complexes of N-heterocyclic carbenes of the present invention may be used as precatalysts in metal-catalyzed cross-coupling reactions.

专利号:US-8124794-B2
优先权日:2002-04-17
标题:Method for the asymmetric synthesis of beta-lactone compounds
发明人：SMITH JEFFREY W; AXELROD FUMIKO; KRIDEL STEVEN J; ROMO DANIEL; PUROHIT VIKRAM; MA GIL
权利人:SMITH JEFFREY W; AXELROD FUMIKO; KRIDEL STEVEN J; ROMO DANIEL; PUROHIT VIKRAM; MA GIL; SANFORD BURNHAM MED RES INST
摘要:The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:US-4656289-A
优先权日:1984-10-25
标 题 :1,3-dibenzyl-4-halohexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one intermediates
发明人：BATES HANS A; ROSENBLUM STUART
权利人:RES FOUNDATION OF STATE UNIV O
摘要:Novel synthetic routes to (3aα,6aα)-1,3-dibenzyl hexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one 5,5-dioxide, a known intermediate in the synthesis of biotin are provided. n A novel synthetic route from this intermediate to biotin is also disclosed.

专利号:US-6005103-A
优先权日:1993-11-19
标题 :Pyrone derivatives as protease inhibitors and antiviral agents
发明人：DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:WARNER LAMBERT CO
摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.