📜4-异丙氧基苯甲醛置于间氯过氧苯甲酸体系中,化学反应生成 4-异丙氧基苯酚 参考文献:(2R)-2-Methylchromane-2-Carboxylic Acids: Discovery Of Selective Pparα Agonists As Hypolipidemic Agents 标题:(2R)-2-Methylchromane-2-Carboxylic Acids: Discovery Of Selective Pparα Agonists As Hypolipidemic Agents 摘要:A Sar Study Was Conducted On Chromane-2-Carboxylic Acid Toward Selective Ppar Alpha Agonisim. As A Result,Highly Potent,And Selective Ppar Alpha Agonists Were Discovered. The Optimized Compound 43 Exhibited Robust Lowering Of Total Cholesterol Levels In Hamster And Dog Animal Models. (C) 2005 Elsevier Ltd. All Rights Reserved. DOI:10.1016/j.Bmcl.2005.05.028
专利号:US-4599461-A 优先权日:1984-01-20 标题 :Process for the synthesis of o-isopropoxyphenol 发明人:MAGGIONI PAOLO; MINISCI FRANCESCO; CORREALE MARIANO 权利人:BRICHIMA SPA 摘要:A process for preparing o-isopropoxyphenol (I) by means of the reaction: in which X is a halogen atom and in which the pyrocatechol (II) is reacted with the isopropyl halide (III) in the presence of an alkaline base in the solid state and of a solid-liquid phase transfer catalyst, in a reaction medium constituted by one or more organic solvents. The catalyst is constituted by a quaternary ammonium or phosphonium salt. The reaction is conducted in a nitrogen atmosphere, at atmospheric pressure, under agitation, at a temperature of preferably between 50 DEG C. and 130 DEG C.
专利号:US-4797427-A 优先权日:1987-04-25 标题:Aromatic diamines containing sulfonic acid aryl esters, a process for their production and their use in the production of polyurethane plastics 发明人:SANDERS JOSEF; REIFF HELMUT; BALLE GERHARD; DIETERICH DIETER 权利人:BAYER AG 摘要:The present invention is directed to new aromatic diamines containing sulfonic acid aryl esters corresponding to the formula wherein R1 represents hydrogen, an optionally branched C1-C6 alkyl radical (preferably a methyl group), a C1-C6 alkoxy radical or a halogen atom (preferably chlorine) and R2 and R3 which may be the same or different, represent hydrogen, an optionally branched C1-C20 (preferably C1-C6) alkyl radical, a C1-C6 alkoxy radical or a halogen atom (preferably chlorine). The present invention is also directed to a process for the production of the above aromatic diamines containing sulfonic acid esters by the reaction of optionally substituted sulfochlorides with optionally substituted phenols followed by hydrogenation. Finally, the present invention is directed to the use of aromatic diamines containing sulfonic acid aryl esters as a synthesis component for the production of polyurethane plastics by the isocyanate polyaddition process.
专利号:CN-87101306-A 优先权日:1987-02-26 标题 :Synthesis of 2-isopropoxyphenol
专利号:EP-0151392-B1 优先权日:1984-01-20 标 题 :New process for the synthesis of o-isopropoxyphenol
专利号:EP-0151392-A2 优先权日:1984-01-20 标 题:New process for the synthesis of o-isopropoxyphenol
专利号:US-2023383342-A1 优先权日:2022-05-31 标 题 :Compositions and methods for nucleic acid sequencing 发明人:WU XIAOLIN; MCCAULEY PATRICK; DHARMARWARDANA MADUSHANI; NIRANTAR SAURABH; GOLYNSKIY MISHA; YANG XIANGYUAN; NEELAKANDAN RAMESH; MACKWORTH BENEDICT; ANASTASI CAROLE; KARUNAKARAN AATHAVAN; VESSERE GERY M; BRACHER DAVID 权利人:ILLUMINA CAMBRIDGE LTD; ILLUMINA SINGAPORE PTE LTD; ILLUMINA INC; ILLUMINA SOFTWARE INC 摘要:Embodiments of the present disclosure relate to kits, compositions, and methods for nucleic acid sequencing, for example, two-channel nucleic acid sequencing by synthesis using blue and green light excitation. In particular, unlabeled nucleotides for incorporation may be used in conjunction with affinity reagents containing detectable labels excitable by blue and/or green lights, for specific binding to each type of nucleotides incorporated.
参考文献:10.1016/j.bmc.2008.11.040 摘要:Pérez-Garrido A, Morales Helguera A, Abellán Guillén A, Cordeiro MN, Garrido Escudero A. Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins. Bioorg Med Chem. 2009 Jan 15;17(2):896–904. doi: 10.1016/j.bmc.2008.11.040.