CAS: 67492-50-6; 3,5-Dichlorophenylboronic Acid

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CAS号541-73-1 间二氯苯 | CAS号19752-55-7 3,5-二氯-1-溴苯 | CAS号5419-55-6 硼酸三异丙酯 | CAS号3032-81-3 3,5-二氯碘苯 | CAS号68716-51-8 3,5-二氯苯硼酸频哪醇酯 | CAS号34883-41-5 3,5-二氯联苯 | CAS号33284-52-5 3,3',5,5'-四氯联苯 | CAS号6575-00-4 3,5-二氯苯腈 | CAS号68716-51-8 3,5-二氯苯硼酸频哪醇酯 | CAS号221018-04-8 4-3 ,5-二氯苯基苯甲醛 | CAS号864725-22-4 1,3-二氯-5-(1-三氟甲... | CAS号99907-90-1 O-(3,5-二氯苯基)羟胺 | CAS号54023-17-5 5-(3,5-二氯苯基)呋喃-...

1,3-二氯苯置于[ir(Cod)(Ome)]2 Sodium Periodate,4,4'-二叔丁基-2,2'-二吡啶体系中,用 四氢呋喃,水 作为反应溶剂,化学反应 20.25H,反应生成 3,5-二氯苯硼酸
参考文献:One-Pot Synthesis Of Arylboronic Acids And Aryl Trifluoroborates By Ir-Catalyzed Borylation Of Arenes
标题:One-Pot Synthesis Of Arylboronic Acids And Aryl Trifluoroborates By Ir-Catalyzed Borylation Of Arenes
摘要:The Synthesis Of Arylboronic Acids And Aryl Trifluoroborates In A One-Pot Sequence By Ir-Catalyzed Borylation Of Arenes Is Reported. To Prepare The Arylboronic Acids,The Ir-Catalyzed Borylation Is Followed By Oxidative Cleavage Of The Boronic Ester With Naio4. To Prepare The Aryltrifluoroborate,The Ir-Catalyzed Borylation Is Followed By Displacement Of Pinacol By Khf2. These Two-Step Sequences Give Products That Are More Reactive Toward Subsequent Chemistry Than The Initially Formed Pinacol Boronates.
DOI:10.1021/ol062903O

专利信息

专利号:US-12150934-B2
优先权日:2016-11-30
标 题 :Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases
发明人：SIDDIQUI ARSHAD M; CIBLAT STEPHANE; CONSTANTINEAU-FORGET LEA; GRAND-MAITRE CHANTAL; GUO XIANGYU; SRIVASTAVA SANJAY; SHIPPS GERALD W; COOPER ALAN B; OZA VIBHA; KOSTURA MATTHEW W; LUTHER MICHAEL; LEVINE JEDD
权利人:BANTAM PHARMACEUTICAL LLC
摘要:Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by “aâ€?, R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

专利号:US-2008119515-A1
优先权日:2003-03-10
标题:Heterocyclic Kinase Inhibitors: Methods of Use and Synthesis
发明人：SIDDIQUI M ARSHAD; BELANGER DAVID B; DAI CHAOYANG; ZHAO LIANYUN
权利人:SIDDIQUI M ARSHAD; BELANGER DAVID B; DAI CHAOYANG; ZHAO LIANYUN
摘要:Inhibitors of kinases, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making kinase inhibitor compounds, methods of inhibiting kinase activity, and methods for treating disease or disease symptom.

专利号:WO-2004080463-A1
优先权日:2003-03-10
标题 :Heterocyclic kinase inhibitors: methods of use and synthesis
发明人：SIDDIQUI M ARSHAD; BELANGER DAVID; DAI CHAOYANG; ZHAO LIANYUN
权利人:NEOGENESIS PHARMACEUTICALS INC; SIDDIQUI M ARSHAD; BELANGER DAVID; DAI CHAOYANG; ZHAO LIANYUN
摘要:Inhibitors of kinases, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making kinase inhibitor compounds, methods of inhibiting kinase activity, and methods for treating disease or disease symptom.

专利号:WO-2025068371-A1
优先权日:2023-09-28
标 题:Inhibitors of the proprotein convertase furin, methods of production thereof and use
发明人：STEINMETZER TORSTEN; LANGE ROMAN WERNER; BOLLER CHARLOTTE; FRIEBERTSHÄUSER EVA; BLOCH KONSTANTIN
权利人:PHILIPPS UNIV MARBURG
摘要:The invention relates to novel inhibitors of the serine protease furin and to related furin-like proprotein convertases according to claim 1, and to methods of synthesis thereof and to use for production of medicaments for treatment of furin-dependent viral and bacterial infection diseases, and other disorders involving furin, such as cystic fibrosis, cancer, osteoarthritis, hypertension, and neurodegenerative disorders.

专利号:US-2009306392-A1
优先权日:2007-10-19
标题 :Gsm intermediates
发明人：HO CHIH YUNG
权利人:HO CHIH YUNG
摘要:The present invention relates the use of compounds having the general Formula I, wherein the definitions or R 1 and R 2 are provided in the specification. Said compounds of Formula I are useful for the synthesis of a variety of γ-secretase modulators, which are in turn useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.

专利号:JP-2010222357-A
优先权日:2002-03-11
标题 :Intermediate compounds for the synthesis of aminoindazole derivatives