参考标题:Microbial Biosynthesis Of Medium-Chain 1-Alkenes By A Nonheme Iron Oxidase 作者:Zhe Rui,Xin Li,Xuejun Zhu,Joyce Liu,Bonnie Domigan,Ian Barr,Jamie H. D. Cate,Wenjun Zhang |发布日期:2014.12.23 摘要:We Have Solved A Long-Standing Mystery Of The Biosynthetic Origin Of 1-Undecene, A Ubiquitous Hydrocarbon Semivolatile Metabolite Of Pseudomonas . Our Study Revealed An Unprecedented Family Of Nonheme Oxidases That Specifically Convert Medium-Chain Fatty Acids Into The Corresponding Terminal Olefins Using An Oxygen-Activating, Nonheme Iron-Dependent Mechanism. Our Findings Unveil Previously Unidentified Chemistry In The Nonheme Fe(II) Enzyme Family, Aid The Functional Study Of This Ubiquitous Metabolite In Pseudomonas , Expand The Scarce Enzyme Inventory For The Transformation Of Fatty Acid Precursors To Hydrocarbons, And Serve As The Basis For Engineering Efforts To Establish Bioprocesses To Produce Medium-Chain Terminal Olefins, Useful As Fuels And Chemical Building Blocks, From Renewable Resources.
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参考文献:10.1007/s00216-018-1467-y 摘要:Borden SA, Damer HN, Krogh ET, Gill CG. Direct quantitation and characterization of fatty acids in salmon tissue by condensed phase membrane introduction mass spectrometry (CP-MIMS) using a modified donor phase. Analytical and Bioanalytical Chemistry. 2018 Nov 23;411(2):291–303. doi: 10.1007/s00216-018-1467-y.